Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer

Surinder M. Soond; Maria V Kozhevnikova; Paul Townsend; Andrey A Zamyatnin

doi:10.3390/ph12020087

Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer

Surinder M. Soond, Maria V Kozhevnikova, Paul Townsend, Andrey A Zamyatnin

Division of Cancer Sciences (L5)

Research output: Contribution to journal › Review article › peer-review

Abstract

In keeping with recent developments in basic research; the importance of the Cathepsins as targets in cancer therapy have taken on increasing importance and given rise to a number of key areas of interest in the clinical setting. In keeping with driving basic research in this area in a translational direction; recent findings have given rise to a number of exciting developments in the areas of cancer diagnosis; prognosis and therapeutic development. As a fast-moving area of research; the focus of this review brings together the latest findings and highlights the translational significance of these developments.

Original language	English
Number of pages	14
Journal	Pharmaceuticals (Basel, Switzerland)
Volume	12
Issue number	2
DOIs	https://doi.org/10.3390/ph12020087
Publication status	Published - 11 Jun 2019

Research Beacons, Institutes and Platforms

Manchester Cancer Research Centre

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/ph12020087Licence: CC BY

Cite this

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abstract = "In keeping with recent developments in basic research; the importance of the Cathepsins as targets in cancer therapy have taken on increasing importance and given rise to a number of key areas of interest in the clinical setting. In keeping with driving basic research in this area in a translational direction; recent findings have given rise to a number of exciting developments in the areas of cancer diagnosis; prognosis and therapeutic development. As a fast-moving area of research; the focus of this review brings together the latest findings and highlights the translational significance of these developments.",

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AU - Zamyatnin, Andrey A

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N2 - In keeping with recent developments in basic research; the importance of the Cathepsins as targets in cancer therapy have taken on increasing importance and given rise to a number of key areas of interest in the clinical setting. In keeping with driving basic research in this area in a translational direction; recent findings have given rise to a number of exciting developments in the areas of cancer diagnosis; prognosis and therapeutic development. As a fast-moving area of research; the focus of this review brings together the latest findings and highlights the translational significance of these developments.

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DO - 10.3390/ph12020087

M3 - Review article

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JO - Pharmaceuticals (Basel, Switzerland)

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Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer

Abstract

Research Beacons, Institutes and Platforms

UN SDGs

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