Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study

Xue Bai; Ahmed Shaheen; Charlotte Grieco; Paolo D. d’Arienzo; Florentia Mina; Juliane A. Czapla; Aleigha R. Lawless; Eleonora Bongiovanni; Umberto Santaniello; Helena Zappi; Dominika Dulak; Andrew Williamson; Rebecca Lee; Avinash Gupta; Caili Li; Lu Si; Martina Ubaldi; Naoya Yamazaki; Dai Ogata; Rebecca Johnson; Benjamin C. Park; Seungyeon Jung; Gabriele Madonna; Juliane Hochherz; Yoshiyasu Umeda; Yasuhiro Nakamura; Christoffer Gebhardt; Lucia Festino; Mariaelena Capone; Paolo Antonio Ascierto; Douglas B. Johnson; Serigne N. Lo; Georgina V. Long; Alexander M. Menzies; Kenjiro Namikawa; Mario Mandala; Jun Guo; Paul Lorigan; Yana G. Najjar; Andrew Haydon; Pietro Quaglino; Genevieve M. Boland; Ryan J. Sullivan; Andrew J.S. Furness; Ruth Plummer; Keith T. Flaherty

doi:10.1016/j.eclinm.2024.102564

Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study

Xue Bai, Ahmed Shaheen, Charlotte Grieco, Paolo D. d’Arienzo, Florentia Mina, Juliane A. Czapla, Aleigha R. Lawless, Eleonora Bongiovanni, Umberto Santaniello, Helena Zappi, Dominika Dulak, Andrew Williamson, Rebecca Lee, Avinash Gupta, Caili Li, Lu Si, Martina Ubaldi, Naoya Yamazaki, Dai Ogata, Rebecca JohnsonBenjamin C. Park, Seungyeon Jung, Gabriele Madonna, Juliane Hochherz, Yoshiyasu Umeda, Yasuhiro Nakamura, Christoffer Gebhardt, Lucia Festino, Mariaelena Capone, Paolo Antonio Ascierto, Douglas B. Johnson, Serigne N. Lo, Georgina V. Long, Alexander M. Menzies, Kenjiro Namikawa, Mario Mandala, Jun Guo, Paul Lorigan, Yana G. Najjar, Andrew Haydon, Pietro Quaglino, Genevieve M. Boland, Ryan J. Sullivan, Andrew J.S. Furness, Ruth Plummer, Keith T. Flaherty

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	EClinicalMedicine
DOIs	https://doi.org/10.1016/j.eclinm.2024.102564
Publication status	Published - May 2024

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10.1016/j.eclinm.2024.102564

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Bai, X., Shaheen, A., Grieco, C., d’Arienzo, P. D., Mina, F., Czapla, J. A., Lawless, A. R., Bongiovanni, E., Santaniello, U., Zappi, H., Dulak, D., Williamson, A., Lee, R., Gupta, A., Li, C., Si, L., Ubaldi, M., Yamazaki, N., Ogata, D., ... Flaherty, K. T. (2024). Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study. EClinicalMedicine. https://doi.org/10.1016/j.eclinm.2024.102564

@article{69428adf00c243bc84ed622b86cce4f0,

title = "Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study",

author = "Xue Bai and Ahmed Shaheen and Charlotte Grieco and d{\textquoteright}Arienzo, {Paolo D.} and Florentia Mina and Czapla, {Juliane A.} and Lawless, {Aleigha R.} and Eleonora Bongiovanni and Umberto Santaniello and Helena Zappi and Dominika Dulak and Andrew Williamson and Rebecca Lee and Avinash Gupta and Caili Li and Lu Si and Martina Ubaldi and Naoya Yamazaki and Dai Ogata and Rebecca Johnson and Park, {Benjamin C.} and Seungyeon Jung and Gabriele Madonna and Juliane Hochherz and Yoshiyasu Umeda and Yasuhiro Nakamura and Christoffer Gebhardt and Lucia Festino and Mariaelena Capone and Ascierto, {Paolo Antonio} and Johnson, {Douglas B.} and Lo, {Serigne N.} and Long, {Georgina V.} and Menzies, {Alexander M.} and Kenjiro Namikawa and Mario Mandala and Jun Guo and Paul Lorigan and Najjar, {Yana G.} and Andrew Haydon and Pietro Quaglino and Boland, {Genevieve M.} and Sullivan, {Ryan J.} and Furness, {Andrew J.S.} and Ruth Plummer and Flaherty, {Keith T.}",

year = "2024",

month = may,

doi = "10.1016/j.eclinm.2024.102564",

language = "English",

journal = "EClinicalMedicine",

issn = "2589-5370",

publisher = "The Lancet",

}

Bai, X, Shaheen, A, Grieco, C, d’Arienzo, PD, Mina, F, Czapla, JA, Lawless, AR, Bongiovanni, E, Santaniello, U, Zappi, H, Dulak, D, Williamson, A, Lee, R, Gupta, A, Li, C, Si, L, Ubaldi, M, Yamazaki, N, Ogata, D, Johnson, R, Park, BC, Jung, S, Madonna, G, Hochherz, J, Umeda, Y, Nakamura, Y, Gebhardt, C, Festino, L, Capone, M, Ascierto, PA, Johnson, DB, Lo, SN, Long, GV, Menzies, AM, Namikawa, K, Mandala, M, Guo, J, Lorigan, P, Najjar, YG, Haydon, A, Quaglino, P, Boland, GM, Sullivan, RJ, Furness, AJS, Plummer, R & Flaherty, KT 2024, 'Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study', EClinicalMedicine. https://doi.org/10.1016/j.eclinm.2024.102564

TY - JOUR

T1 - Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study

AU - Bai, Xue

AU - Shaheen, Ahmed

AU - Grieco, Charlotte

AU - d’Arienzo, Paolo D.

AU - Mina, Florentia

AU - Czapla, Juliane A.

AU - Lawless, Aleigha R.

AU - Bongiovanni, Eleonora

AU - Santaniello, Umberto

AU - Zappi, Helena

AU - Dulak, Dominika

AU - Williamson, Andrew

AU - Lee, Rebecca

AU - Gupta, Avinash

AU - Li, Caili

AU - Si, Lu

AU - Ubaldi, Martina

AU - Yamazaki, Naoya

AU - Ogata, Dai

AU - Johnson, Rebecca

AU - Park, Benjamin C.

AU - Jung, Seungyeon

AU - Madonna, Gabriele

AU - Hochherz, Juliane

AU - Umeda, Yoshiyasu

AU - Nakamura, Yasuhiro

AU - Gebhardt, Christoffer

AU - Festino, Lucia

AU - Capone, Mariaelena

AU - Ascierto, Paolo Antonio

AU - Johnson, Douglas B.

AU - Lo, Serigne N.

AU - Long, Georgina V.

AU - Menzies, Alexander M.

AU - Namikawa, Kenjiro

AU - Mandala, Mario

AU - Guo, Jun

AU - Lorigan, Paul

AU - Najjar, Yana G.

AU - Haydon, Andrew

AU - Quaglino, Pietro

AU - Boland, Genevieve M.

AU - Sullivan, Ryan J.

AU - Furness, Andrew J.S.

AU - Plummer, Ruth

AU - Flaherty, Keith T.

PY - 2024/5

Y1 - 2024/5

UR - http://dx.doi.org/10.1016/j.eclinm.2024.102564

U2 - 10.1016/j.eclinm.2024.102564

DO - 10.1016/j.eclinm.2024.102564

M3 - Article

SN - 2589-5370

JO - EClinicalMedicine

JF - EClinicalMedicine

ER -

Dabrafenib plus trametinib versus anti-PD-1 monotherapy as adjuvant therapy in BRAF V600-mutant stage III melanoma after definitive surgery: a multicenter, retrospective cohort study

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