TY - JOUR
T1 - Database of queryable gene expression patterns for Xenopus
AU - Gilchrist, Michael J.
AU - Christensen, Mikkel B.
AU - Bronchain, Odile J.
AU - Brunet, Frédéric
AU - Chesneau, Albert
AU - Fenger, Ursula
AU - Geach, Timothy J.
AU - Ironfield, Holly V.
AU - Kaya, Ferdinand
AU - Kricha, Sadia
AU - Lea, Robert
AU - Massé, Karine
AU - Néant, Isabelle
AU - Paillard, Elodie
AU - Parain, Karine
AU - Perron, Muriel
AU - Sinzelle, Ludivine
AU - Souopgui, Jacob
AU - Thuret, Raphael
AU - Ymlahi-Ouazzani, Qods
AU - Pollet, Nicolas
PY - 2009/6/1
Y1 - 2009/6/1
N2 - The precise localization of gene expression within the developing embryo, and how it changes over time, is one of the most important sources of information for elucidating gene function. As a searchable resource, this information has up until now been largely inaccessible to the Xenopus community. Here, we present a new database of Xenopus gene expression patterns, queryable by specific location or region in the embryo. Pattern matching can be driven either from an existing in situ image, or from a user-defined pattern based on development stage schematic diagrams. The data are derived from the work of a group of 21 Xenopus researchers over a period of 4 days. We used a novel, rapid manual annotation tool, XenMARK, which exploits the ability of the human brain to make the necessary distortions in transferring data from the in situ images to the standard schematic geometry. Developmental Dynamics 238:1379-1388, 2009. (c) 2009 Wiley-Liss, Inc.
AB - The precise localization of gene expression within the developing embryo, and how it changes over time, is one of the most important sources of information for elucidating gene function. As a searchable resource, this information has up until now been largely inaccessible to the Xenopus community. Here, we present a new database of Xenopus gene expression patterns, queryable by specific location or region in the embryo. Pattern matching can be driven either from an existing in situ image, or from a user-defined pattern based on development stage schematic diagrams. The data are derived from the work of a group of 21 Xenopus researchers over a period of 4 days. We used a novel, rapid manual annotation tool, XenMARK, which exploits the ability of the human brain to make the necessary distortions in transferring data from the in situ images to the standard schematic geometry. Developmental Dynamics 238:1379-1388, 2009. (c) 2009 Wiley-Liss, Inc.
KW - Xenopus
KW - gene expression
KW - gene expression pattern analysis
KW - in situ images
KW - image annotation
KW - database
KW - Information Storage and Retrieval
UR - https://doi.org/10.1002/dvdy.21940
U2 - 10.1002/dvdy.21940
DO - 10.1002/dvdy.21940
M3 - Article
C2 - 19347954
SN - 1058-8388
VL - 238
SP - 1379
EP - 1388
JO - Developmental dynamics : an official publication of the American Association of Anatomists
JF - Developmental dynamics : an official publication of the American Association of Anatomists
IS - 6
ER -