Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

Grzegorz Gondek; Teng Li; Richard J M Lynch; Richard J. Dewhurst

doi:10.1117/1.2360690

Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

Grzegorz Gondek, Teng Li, Richard J M Lynch, Richard J. Dewhurst

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the phenomenon of a sudden decrease in the, amplitude of photoacoustic signals arising from nanosecond laser pulse irradiation of biological samples, measured in vitro. Several dental enamel and chicken/turkey breast samples are examined. Moderate optical energy densities (i.e., about 300 mJ/cm2) are used, typical of those exploited in photoacoustic investigations. Measurements show a rapid decay of photoacoustic signals within the first few laser pulses absorbed by the sample. This phenomenon indicates that laser irradiation interacts with biological samples, causing long-term physical changes that can be attributed to a reduction of optical absorption within the samples. © 2006 Society of Photo-Optical Instrumentation Engineers.

Original language	English
Article number	054036
Journal	Journal of Biomedical Optics
Volume	11
Issue number	5
DOIs	https://doi.org/10.1117/1.2360690
Publication status	Published - Sept 2006

Keywords

Laser ultrasound
Nondestructive examination
Photoacoustics

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10.1117/1.2360690

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title = "Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses",

abstract = "We describe the phenomenon of a sudden decrease in the, amplitude of photoacoustic signals arising from nanosecond laser pulse irradiation of biological samples, measured in vitro. Several dental enamel and chicken/turkey breast samples are examined. Moderate optical energy densities (i.e., about 300 mJ/cm2) are used, typical of those exploited in photoacoustic investigations. Measurements show a rapid decay of photoacoustic signals within the first few laser pulses absorbed by the sample. This phenomenon indicates that laser irradiation interacts with biological samples, causing long-term physical changes that can be attributed to a reduction of optical absorption within the samples. {\textcopyright} 2006 Society of Photo-Optical Instrumentation Engineers.",

keywords = "Laser ultrasound, Nondestructive examination, Photoacoustics",

author = "Grzegorz Gondek and Teng Li and Lynch, {Richard J M} and Dewhurst, {Richard J.}",

year = "2006",

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language = "English",

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journal = "Journal of Biomedical Optics",

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T1 - Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

AU - Gondek, Grzegorz

AU - Li, Teng

AU - Lynch, Richard J M

AU - Dewhurst, Richard J.

PY - 2006/9

Y1 - 2006/9

N2 - We describe the phenomenon of a sudden decrease in the, amplitude of photoacoustic signals arising from nanosecond laser pulse irradiation of biological samples, measured in vitro. Several dental enamel and chicken/turkey breast samples are examined. Moderate optical energy densities (i.e., about 300 mJ/cm2) are used, typical of those exploited in photoacoustic investigations. Measurements show a rapid decay of photoacoustic signals within the first few laser pulses absorbed by the sample. This phenomenon indicates that laser irradiation interacts with biological samples, causing long-term physical changes that can be attributed to a reduction of optical absorption within the samples. © 2006 Society of Photo-Optical Instrumentation Engineers.

AB - We describe the phenomenon of a sudden decrease in the, amplitude of photoacoustic signals arising from nanosecond laser pulse irradiation of biological samples, measured in vitro. Several dental enamel and chicken/turkey breast samples are examined. Moderate optical energy densities (i.e., about 300 mJ/cm2) are used, typical of those exploited in photoacoustic investigations. Measurements show a rapid decay of photoacoustic signals within the first few laser pulses absorbed by the sample. This phenomenon indicates that laser irradiation interacts with biological samples, causing long-term physical changes that can be attributed to a reduction of optical absorption within the samples. © 2006 Society of Photo-Optical Instrumentation Engineers.

KW - Laser ultrasound

KW - Nondestructive examination

KW - Photoacoustics

U2 - 10.1117/1.2360690

DO - 10.1117/1.2360690

M3 - Article

SN - 1083-3668

VL - 11

JO - Journal of Biomedical Optics

JF - Journal of Biomedical Optics

IS - 5

M1 - 054036

ER -

Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

Abstract

Keywords

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