Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window

L. M. Maestro; J. E. Ramirez-Hernandez; N. Bogdan; J. A. Capobianco; F. Vetrone; J. Garcia Sole; D. Jaque

doi:10.1039/c1nr11285f

Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window

L. M. Maestro, J. E. Ramirez-Hernandez, N. Bogdan, J. A. Capobianco, F. Vetrone, J. Garcia Sole, D. Jaque

Research output: Contribution to journal › Article › peer-review

Abstract

A new approach to deep tissue imaging is presented based on 8 nm CdTe semiconductor quantum dots (QDs). The characteristic 800 nm emission was found to be efficiently excited via two-photon absorption of 900 nm photons. The fact that both excitation and emission wavelengths lie within the "biological window" allows for high resolution fluorescence imaging at depths close to 2 mm. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal sensitivity of CdTe-QDs, one may envisage, in the near future, their use in high resolution deep-tissue thermal imaging.

Original language	English
Pages (from-to)	298-302
Number of pages	5
Journal	Nanoscale
Volume	4
Issue number	1
DOIs	https://doi.org/10.1039/c1nr11285f
Publication status	Published - 2012

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title = "Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window",

abstract = "A new approach to deep tissue imaging is presented based on 8 nm CdTe semiconductor quantum dots (QDs). The characteristic 800 nm emission was found to be efficiently excited via two-photon absorption of 900 nm photons. The fact that both excitation and emission wavelengths lie within the {"}biological window{"} allows for high resolution fluorescence imaging at depths close to 2 mm. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal sensitivity of CdTe-QDs, one may envisage, in the near future, their use in high resolution deep-tissue thermal imaging.",

author = "Maestro, {L. M.} and Ramirez-Hernandez, {J. E.} and N. Bogdan and Capobianco, {J. A.} and F. Vetrone and {Garcia Sole}, J. and D. Jaque",

year = "2012",

doi = "10.1039/c1nr11285f",

language = "English",

volume = "4",

pages = "298--302",

journal = "Nanoscale",

issn = "2040-3364",

publisher = "Royal Society of Chemistry",

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T1 - Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window

AU - Maestro, L. M.

AU - Ramirez-Hernandez, J. E.

AU - Bogdan, N.

AU - Capobianco, J. A.

AU - Vetrone, F.

AU - Garcia Sole, J.

AU - Jaque, D.

PY - 2012

Y1 - 2012

N2 - A new approach to deep tissue imaging is presented based on 8 nm CdTe semiconductor quantum dots (QDs). The characteristic 800 nm emission was found to be efficiently excited via two-photon absorption of 900 nm photons. The fact that both excitation and emission wavelengths lie within the "biological window" allows for high resolution fluorescence imaging at depths close to 2 mm. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal sensitivity of CdTe-QDs, one may envisage, in the near future, their use in high resolution deep-tissue thermal imaging.

AB - A new approach to deep tissue imaging is presented based on 8 nm CdTe semiconductor quantum dots (QDs). The characteristic 800 nm emission was found to be efficiently excited via two-photon absorption of 900 nm photons. The fact that both excitation and emission wavelengths lie within the "biological window" allows for high resolution fluorescence imaging at depths close to 2 mm. These penetration depths have been used to obtain the first deep tissue multiphoton excited fluorescence image based on CdTe-QDs. Due to the large thermal sensitivity of CdTe-QDs, one may envisage, in the near future, their use in high resolution deep-tissue thermal imaging.

U2 - 10.1039/c1nr11285f

DO - 10.1039/c1nr11285f

M3 - Article

SN - 2040-3364

VL - 4

SP - 298

EP - 302

JO - Nanoscale

JF - Nanoscale

IS - 1

ER -

Deep tissue bio-imaging using two-photon excited CdTe fluorescent quantum dots working within the biological window

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