Dendritic cell research projects.

Pierre Aeby; David Basketter; Walter Diembeck; Dietmar Eschrich; Frank Gerberick; Hiroshi Itagaki; Ian Kimber; Beatrice Le Varlet; Irene Manou; Marc Paye; Francoise Rousset; Joanna Rowland; Hitoshi Sakaguchi

Dendritic cell research projects.

Pierre Aeby, David Basketter, Walter Diembeck, Dietmar Eschrich, Frank Gerberick, Hiroshi Itagaki, Ian Kimber, Beatrice Le Varlet, Irene Manou, Marc Paye, Francoise Rousset, Joanna Rowland, Hitoshi Sakaguchi

Research output: Contribution to journal › Article › peer-review

Abstract

The Colipa Skin Tolerance Task Force (STTF) is playing an active role in promoting refined methods for in vivo sensitisation tests. Dendritic cells (DCs), whose central role during the induction phase of skin sensitisation is well documented, were perceived as promising in vitro test systems. DC research projects supported by STTF evaluated the relevance of IL-1beta mRNA expression or changes in gene expression using gene microarrays for predicting potential sensitisers. Myeloid cell lines are being evaluated as surrogate DCs. Intracellular signal transduction pathways are being explored in order to understand the underlying biological mechanisms.

Original language	English
Journal	ALTEX : Alternativen zu Tierexperimenten
Volume	23 Suppl
Publication status	Published - 2006

Cite this

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title = "Dendritic cell research projects.",

abstract = "The Colipa Skin Tolerance Task Force (STTF) is playing an active role in promoting refined methods for in vivo sensitisation tests. Dendritic cells (DCs), whose central role during the induction phase of skin sensitisation is well documented, were perceived as promising in vitro test systems. DC research projects supported by STTF evaluated the relevance of IL-1beta mRNA expression or changes in gene expression using gene microarrays for predicting potential sensitisers. Myeloid cell lines are being evaluated as surrogate DCs. Intracellular signal transduction pathways are being explored in order to understand the underlying biological mechanisms.",

author = "Pierre Aeby and David Basketter and Walter Diembeck and Dietmar Eschrich and Frank Gerberick and Hiroshi Itagaki and Ian Kimber and {Le Varlet}, Beatrice and Irene Manou and Marc Paye and Francoise Rousset and Joanna Rowland and Hitoshi Sakaguchi",

year = "2006",

language = "English",

volume = "23 Suppl",

journal = "ALTEX : Alternativen zu Tierexperimenten",

issn = "0946-7785",

publisher = "Elsevier BV",

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TY - JOUR

T1 - Dendritic cell research projects.

AU - Aeby, Pierre

AU - Basketter, David

AU - Diembeck, Walter

AU - Eschrich, Dietmar

AU - Gerberick, Frank

AU - Itagaki, Hiroshi

AU - Kimber, Ian

AU - Le Varlet, Beatrice

AU - Manou, Irene

AU - Paye, Marc

AU - Rousset, Francoise

AU - Rowland, Joanna

AU - Sakaguchi, Hitoshi

PY - 2006

Y1 - 2006

N2 - The Colipa Skin Tolerance Task Force (STTF) is playing an active role in promoting refined methods for in vivo sensitisation tests. Dendritic cells (DCs), whose central role during the induction phase of skin sensitisation is well documented, were perceived as promising in vitro test systems. DC research projects supported by STTF evaluated the relevance of IL-1beta mRNA expression or changes in gene expression using gene microarrays for predicting potential sensitisers. Myeloid cell lines are being evaluated as surrogate DCs. Intracellular signal transduction pathways are being explored in order to understand the underlying biological mechanisms.

AB - The Colipa Skin Tolerance Task Force (STTF) is playing an active role in promoting refined methods for in vivo sensitisation tests. Dendritic cells (DCs), whose central role during the induction phase of skin sensitisation is well documented, were perceived as promising in vitro test systems. DC research projects supported by STTF evaluated the relevance of IL-1beta mRNA expression or changes in gene expression using gene microarrays for predicting potential sensitisers. Myeloid cell lines are being evaluated as surrogate DCs. Intracellular signal transduction pathways are being explored in order to understand the underlying biological mechanisms.

M3 - Article

C2 - 17492184

SN - 0946-7785

VL - 23 Suppl

JO - ALTEX : Alternativen zu Tierexperimenten

JF - ALTEX : Alternativen zu Tierexperimenten

ER -

Dendritic cell research projects.

Abstract

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