Depression in older persons with versus without vascular disease in the open population: similar depressive symptom patterns, more disability.

Els Licht-Strunk, Marijke A Bremmer, Harm Van Marwijk, Dorly J H Deeg, Witte J G Hoogendijk, Marten {De Haan}, Willem {Van Tilburg}, Aartjan T F Beekman

    Research output: Contribution to journalArticlepeer-review


    BACKGROUND: Clinical studies suggest that vascular depression presents with typical symptom patterns. The aim of the present study is to examine whether depressed older persons in the open population with and without vascular disease show different symptom patterns. METHODS: In the Longitudinal Aging Study Amsterdam (LASA), a depressed cohort with (n=114) and without (n=292) vascular disease was identified. Depression was measured using self-reports (CES-D). Vascular disease was confirmed or ruled out using a combination of self-reported data, medication use and reports from general practitioners. RESULTS: No significant differences were found in depressive symptom patterns, in symptom clusters nor individual items of the CES-D. Depressed subjects with vascular disease showed much more disability than those without vascular disease. Age of onset of depression did not show statistically significant difference. CONCLUSIONS: From our study in the open population, there is no evidence to support the hypothesis that depressed older persons with vascular disease have a distinct depressive symptom profile, but they do show more disability.
    Original languageEnglish
    Pages (from-to)155-160
    Number of pages6
    JournalJournal of Affective Disorders
    Publication statusPublished - 2004


    • 80 over
    • activities daily living
    • activities daily living psychology
    • aged
    • cardiovascular diseases
    • cardiovascular diseases diagnosis
    • cardiovascular diseases epidemiology
    • cardiovascular diseases psychology
    • causality
    • comorbidity
    • cross sectional studies
    • dementia
    • depressive disorder
    • depressive disorder diagnosis
    • depressive disorder epidemiology
    • depressive disorder psychology
    • disability evaluation
    • female
    • geriatric assessment
    • geriatric assessment statistics {\&} numerical data
    • humans
    • longitudinal studies
    • male
    • middle aged
    • motivation
    • netherlands
    • personality assessment
    • risk factors
    • statistics topic
    • vascular
    • vascular diagnosis
    • vascular epidemiology
    • vascular psychology


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