Deprotonation-electrophile trapping of terminal epoxides

David M. Hodgson, E. H M Kirton, Steven M. Miles, S. L M Norsikian, Nigel J. Reynolds, Steven J. Coote

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Organolithium-induced deprotonation of terminal epoxides in the presence of appropriate diamine ligands allows trapping with a range of electrophiles, yielding functionalised di- and tri-substituted epoxides in good yields and with control of stereochemistry at the epoxide. © The Royal Society of Chemistry 2005.
    Original languageEnglish
    Pages (from-to)1893-1904
    Number of pages11
    JournalOrganic and Biomolecular Chemistry
    Volume3
    Issue number10
    Publication statusPublished - 21 May 2005

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