Design, fabrication and initial evaluation of a novel hybrid system for tissue engineering applications

Fengyuan Liu; Srichand Hinduja; Paulo Jorge Da Silva Bartolo

doi:10.1016/j.procir.2017.04.030

Design, fabrication and initial evaluation of a novel hybrid system for tissue engineering applications

Fengyuan Liu, Srichand Hinduja, Paulo Jorge Da Silva Bartolo

Research output: Contribution to journal › Article › peer-review

Abstract

A novel hybrid biomanufacturing system, called Plasma-assisted Bioextrusion System (PABS), has been developed to produce multi-material and functional graded scaffolds for tissue engineering applications. It combines pressure-assisted extrusion heads, screw-assisted extrusion heads and plasma jets, allowing surface of printed scaffolds matching the characteristics of the surrounding tissue. This paper explores this system to produce PCL and PCL/CNT scaffolds for bone applications. Processing conditions were optimized in terms of deposition velocity, screw rotational velocity and the effect of these parameters on the morphological and mechanical properties of produced scaffolds assessed.

Original language	English
Pages (from-to)	213-218
Number of pages	6
Journal	Procedia CIRP
Volume	65
Early online date	21 Jul 2017
DOIs	https://doi.org/10.1016/j.procir.2017.04.030
Publication status	Published - 2017

Access to Document

10.1016/j.procir.2017.04.030

Cite this

@article{7eb0f8b912a94635ba27af2a969f25ff,

title = "Design, fabrication and initial evaluation of a novel hybrid system for tissue engineering applications",

abstract = "A novel hybrid biomanufacturing system, called Plasma-assisted Bioextrusion System (PABS), has been developed to produce multi-material and functional graded scaffolds for tissue engineering applications. It combines pressure-assisted extrusion heads, screw-assisted extrusion heads and plasma jets, allowing surface of printed scaffolds matching the characteristics of the surrounding tissue. This paper explores this system to produce PCL and PCL/CNT scaffolds for bone applications. Processing conditions were optimized in terms of deposition velocity, screw rotational velocity and the effect of these parameters on the morphological and mechanical properties of produced scaffolds assessed.",

author = "Fengyuan Liu and Srichand Hinduja and {Da Silva Bartolo}, {Paulo Jorge}",

year = "2017",

doi = "10.1016/j.procir.2017.04.030",

language = "English",

volume = "65",

pages = "213--218",

journal = "Procedia CIRP",

issn = "2212-8271",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Design, fabrication and initial evaluation of a novel hybrid system for tissue engineering applications

AU - Liu, Fengyuan

AU - Hinduja, Srichand

AU - Da Silva Bartolo, Paulo Jorge

PY - 2017

Y1 - 2017

N2 - A novel hybrid biomanufacturing system, called Plasma-assisted Bioextrusion System (PABS), has been developed to produce multi-material and functional graded scaffolds for tissue engineering applications. It combines pressure-assisted extrusion heads, screw-assisted extrusion heads and plasma jets, allowing surface of printed scaffolds matching the characteristics of the surrounding tissue. This paper explores this system to produce PCL and PCL/CNT scaffolds for bone applications. Processing conditions were optimized in terms of deposition velocity, screw rotational velocity and the effect of these parameters on the morphological and mechanical properties of produced scaffolds assessed.

AB - A novel hybrid biomanufacturing system, called Plasma-assisted Bioextrusion System (PABS), has been developed to produce multi-material and functional graded scaffolds for tissue engineering applications. It combines pressure-assisted extrusion heads, screw-assisted extrusion heads and plasma jets, allowing surface of printed scaffolds matching the characteristics of the surrounding tissue. This paper explores this system to produce PCL and PCL/CNT scaffolds for bone applications. Processing conditions were optimized in terms of deposition velocity, screw rotational velocity and the effect of these parameters on the morphological and mechanical properties of produced scaffolds assessed.

U2 - 10.1016/j.procir.2017.04.030

DO - 10.1016/j.procir.2017.04.030

M3 - Article

SN - 2212-8271

VL - 65

SP - 213

EP - 218

JO - Procedia CIRP

JF - Procedia CIRP

ER -

Design, fabrication and initial evaluation of a novel hybrid system for tissue engineering applications

Abstract

Access to Document

Fingerprint

Cite this