Detection of human herpes virus 6 DNA in fetal hydrops.

Ahmed M. Ashshi, Robert J. Cooper, Paul E. Klapper, Osama Al-Jiffri, Lynette Moore

Research output: Contribution to journalArticlepeer-review

Abstract

Human herpes virus 6 (HHV6) DNA was detected in two of eight fetuses with hydrops and none of ten non-hydropic dead fetuses. Both cases with HHV6 DNA had chromosomal abnormalities. Positive results were confirmed with a second PCR specific for an alternate region of the HHV6 genome. Restriction endonuclease analysis confirmed that the viral DNA was representative of HHV6 type A.
Original languageEnglish
Pages (from-to)1519-1520
Number of pages2
JournalLancet
Volume355( 9214)
Issue number9214
DOIs
Publication statusPublished - 29 Apr 2000

Keywords

  • isolation & purification: DNA, Viral
  • Female
  • Genome, Viral
  • Gestational Age
  • genetics: Herpesvirus 6, Human
  • Humans
  • pathology: Hydrops Fetalis
  • Infant, Newborn
  • Male
  • Polymerase Chain Reaction
  • Restriction Mapping

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