Detection of myocardial infarction in the mini-pig using NMR imaging.

D. Checkley; B. E. Loveday; J. C. Waterton; X. P. Zhu; I. Isherwood

Detection of myocardial infarction in the mini-pig using NMR imaging.

D. Checkley, B. E. Loveday, J. C. Waterton, X. P. Zhu, I. Isherwood

Research output: Contribution to journal › Article › peer-review

Abstract

Spin-echo images of 10 myocardial infarcts in nine mini-pigs were obtained at 30 h, 3 days, and approximately 10 days postinfarction. Infarcts were not detected at all at 30 h in five out of five cases examined. At 3 days postembolization (six cases) one infarct was certainly detected, whilst at 10 days (nine cases) all infarcts were seen as high-signal areas in long TE spin-echo sequences. After 2 weeks no further infarct signal change was detected (three cases), but myocardial thinning became more evident. Using techniques similar to those reported here, early postinfarct changes in the dog have been detected by other authors. Possible reasons for this difference between pig and dog are discussed.

Original language	English
Pages (from-to)	201-216
Number of pages	15
Journal	Magnetic Resonance in Medicine
Volume	5
Issue number	3
Publication status	Published - Sept 1987

Keywords

Animals
Disease Models, Animal
Dogs
Magnetic Resonance Imaging
diagnosis: Myocardial Infarction
Species Specificity
Swine
Swine, Miniature

Cite this

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title = "Detection of myocardial infarction in the mini-pig using NMR imaging.",

abstract = "Spin-echo images of 10 myocardial infarcts in nine mini-pigs were obtained at 30 h, 3 days, and approximately 10 days postinfarction. Infarcts were not detected at all at 30 h in five out of five cases examined. At 3 days postembolization (six cases) one infarct was certainly detected, whilst at 10 days (nine cases) all infarcts were seen as high-signal areas in long TE spin-echo sequences. After 2 weeks no further infarct signal change was detected (three cases), but myocardial thinning became more evident. Using techniques similar to those reported here, early postinfarct changes in the dog have been detected by other authors. Possible reasons for this difference between pig and dog are discussed.",

keywords = "Animals, Disease Models, Animal, Dogs, Magnetic Resonance Imaging, diagnosis: Myocardial Infarction, Species Specificity, Swine, Swine, Miniature",

author = "D. Checkley and Loveday, {B. E.} and Waterton, {J. C.} and Zhu, {X. P.} and I. Isherwood",

year = "1987",

month = sep,

language = "English",

volume = "5",

pages = "201--216",

journal = "Magnetic Resonance in Medicine",

issn = "0740-3194",

publisher = "John Wiley & Sons Ltd",

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}

TY - JOUR

T1 - Detection of myocardial infarction in the mini-pig using NMR imaging.

AU - Checkley, D.

AU - Loveday, B. E.

AU - Waterton, J. C.

AU - Zhu, X. P.

AU - Isherwood, I.

PY - 1987/9

Y1 - 1987/9

N2 - Spin-echo images of 10 myocardial infarcts in nine mini-pigs were obtained at 30 h, 3 days, and approximately 10 days postinfarction. Infarcts were not detected at all at 30 h in five out of five cases examined. At 3 days postembolization (six cases) one infarct was certainly detected, whilst at 10 days (nine cases) all infarcts were seen as high-signal areas in long TE spin-echo sequences. After 2 weeks no further infarct signal change was detected (three cases), but myocardial thinning became more evident. Using techniques similar to those reported here, early postinfarct changes in the dog have been detected by other authors. Possible reasons for this difference between pig and dog are discussed.

AB - Spin-echo images of 10 myocardial infarcts in nine mini-pigs were obtained at 30 h, 3 days, and approximately 10 days postinfarction. Infarcts were not detected at all at 30 h in five out of five cases examined. At 3 days postembolization (six cases) one infarct was certainly detected, whilst at 10 days (nine cases) all infarcts were seen as high-signal areas in long TE spin-echo sequences. After 2 weeks no further infarct signal change was detected (three cases), but myocardial thinning became more evident. Using techniques similar to those reported here, early postinfarct changes in the dog have been detected by other authors. Possible reasons for this difference between pig and dog are discussed.

KW - Animals

KW - Disease Models, Animal

KW - Dogs

KW - Magnetic Resonance Imaging

KW - diagnosis: Myocardial Infarction

KW - Species Specificity

KW - Swine

KW - Swine, Miniature

M3 - Article

SN - 0740-3194

VL - 5

SP - 201

EP - 216

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 3

ER -

Detection of myocardial infarction in the mini-pig using NMR imaging.

Abstract

Keywords

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