Development of a Flexible MIP-Based Biosensor Platform for the Thermal Detection of Neurotransmitters

Kai Betlem, M.P. Down, C.W. Foster, S. Akthar, K. Eersels, B. Van Grinsven, T.J. Cleij, C.E. Banks, M. Peeters

Research output: Chapter in Book/Conference proceedingConference contributionpeer-review

Abstract

We have developed high affinity Molecularly Imprinted Polymers (MIPs) for neurotransmitters such as dopamine, noradrenaline and caffeine. These polymer particles are mixed within the bulk of screen-printed ink allowing masss-producible bulk modified MIP Screen-Printed Electrodes (MIP-SPEs) to be realised. We have explored different SPE supporting surfaces, such as polyester, tracing paper and household-printing paper. The performance of those MIP-SPEs is studied using the Heat-Transfer Method (HTM), a patented thermal method. With the combination of screen-printing techniques and thermal detection, it is possible to develop a portable sensor platform that is capable of low-cost and straightforward detection of biomolecules on-site. In the future, this unique sensor architecture holds great promise for the use in biomedical devices. Copyright © Materials Research Society 2017.
Original languageUndefined
Title of host publicationMRS Advances
Pages1569-1574
Number of pages6
DOIs
Publication statusPublished - 2018

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