Diabetes and Lower-Extremity Diseases

Andrew J M Boulton*, Frank L. Bowling

*Corresponding author for this work

    Research output: Chapter in Book/Conference proceedingChapterpeer-review

    Abstract

    The lifetime risk that a person with diabetes will develop a foot ulcer may be as high as 15%-25%, and every year an estimated 1 million people lose a leg as a consequence of this condition, equating to one amputation every thirty seconds. Diabetic foot ulceration imposes a significant medical, social, and economic burden. Disorders of the foot account for more hospital admissions than any other long-term medical condition and also increase morbidity and mortality. A clear understanding of the etiology and pathogenesis of ulceration is essential if the incidence is to be reduced and subsequent amputation prevented. This chapter presents an overview of the pathway to ulceration.

    Original languageEnglish
    Title of host publicationDiabetes Public Health
    Subtitle of host publicationFrom Data to Policy
    EditorsK M Venkat Narayan, Desmond Williams, Edward W Gregg, Catherine C Cowie
    PublisherOxford University Press
    ISBN (Electronic)9780199871544
    ISBN (Print)9780195317060
    DOIs
    Publication statusPublished - 1 Jan 2011

    Keywords

    • Diabetes
    • Diabetic foot ulceration
    • Foot ulcers
    • Prevention

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