TY - JOUR
T1 - Diabetes-Related Lower Extremity Amputations in Romania
T2 - Patterns and Changes between 2015 and 2019
AU - Coman, Horaţiu
AU - Stancu, Bogdan
AU - Gâvan, Norina A
AU - Bowling, Frank L
AU - Podariu, Laura
AU - Bondor, Cosmina I
AU - Radulian, Gabriela
N1 - Funding Information:
Financial support for this study was provided by the Society of Diabetic Neuropathy.
Publisher Copyright:
© 2022 by the authors.
PY - 2022/12/29
Y1 - 2022/12/29
N2 - Lower extremity amputations (LEAs) are a feared complication of diabetes mellitus (DM). Here we evaluated the recent trends in DM-related LEAs in Romania. We collected data from a national database regarding minor and major LEAs performed between 2015 and 2019 in patients with DM admitted to a public hospital. Absolute numbers of LEAs were presented by year, diabetes type, sex and age; incidence rates of LEAs in the general population were also calculated. Over the study period, 40,499 LEAs were recorded nationwide (83.16% in persons with type 2 DM [T2DM]); on average, the number of LEAs increased by 5.7%/year. This trend was driven by an increased number of LEAs in patients with T2DM; in patients with type 1 DM (T1DM), LEAs decreased over the study period. In patients with T2DM, the increase in minor LEAs was more pronounced than that in major LEAs. The overall number of LEAs showed an increasing trend with age (r = 0.72), which was most pronounced in patients aged ≥70 years. Men had a higher frequency of LEAs than women, regardless of DM type. These data support renewed efforts to prevent and decrease the burden of amputations among patients with DM.
AB - Lower extremity amputations (LEAs) are a feared complication of diabetes mellitus (DM). Here we evaluated the recent trends in DM-related LEAs in Romania. We collected data from a national database regarding minor and major LEAs performed between 2015 and 2019 in patients with DM admitted to a public hospital. Absolute numbers of LEAs were presented by year, diabetes type, sex and age; incidence rates of LEAs in the general population were also calculated. Over the study period, 40,499 LEAs were recorded nationwide (83.16% in persons with type 2 DM [T2DM]); on average, the number of LEAs increased by 5.7%/year. This trend was driven by an increased number of LEAs in patients with T2DM; in patients with type 1 DM (T1DM), LEAs decreased over the study period. In patients with T2DM, the increase in minor LEAs was more pronounced than that in major LEAs. The overall number of LEAs showed an increasing trend with age (r = 0.72), which was most pronounced in patients aged ≥70 years. Men had a higher frequency of LEAs than women, regardless of DM type. These data support renewed efforts to prevent and decrease the burden of amputations among patients with DM.
KW - Male
KW - Humans
KW - Female
KW - Diabetic Foot/epidemiology
KW - Romania/epidemiology
KW - Diabetes Mellitus, Type 2/complications
KW - Amputation, Surgical
KW - Incidence
KW - Lower Extremity/surgery
KW - lower extremity amputation
KW - diabetes mellitus
KW - nationwide study
KW - incidence
U2 - 10.3390/ijerph20010557
DO - 10.3390/ijerph20010557
M3 - Article
C2 - 36612876
SN - 1660-4601
VL - 20
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 1
M1 - 557
ER -