Diagnosis of invasive candidosis by enzyme immunoassay of serum antigen

R. C. Warren, A. Bartlett, D. E. Bidwell, M. D. Richardson, A. Voller, L. O. White

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Enzyme immunoassay was used to measure Candida albicans-related antigen in sera of rabbits and mice infected with C albicans. A range of heterologous antigens tested gave no cross reactions. Of the 3 patients who were investigated and gave positive reactions, 2 were confirmed as having deep candida infections. Enzyme immunoassay is efficient, simple, and sensitive, and may prove valuable in the early diagnosis of invasive candida infections.
    Original languageEnglish
    Pages (from-to)1183-1185
    Number of pages2
    JournalBmj
    Volume1
    Issue number6070
    Publication statusPublished - 1977

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