Differences in heart rate variability between depressed and non-depressed elderly.

Koen G {Van der Kooy}; Hein P J {Van Hout}; Harm Van Marwijk; Marten {De Haan}; Coen D A Stehouwer; Aartjan T F Beekman

Differences in heart rate variability between depressed and non-depressed elderly.

Koen G {Van der Kooy}, Hein P J {Van Hout}, Harm Van Marwijk, Marten {De Haan}, Coen D A Stehouwer, Aartjan T F Beekman

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD: A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched for age and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. RESULTS: Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. CONCLUSION: Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

Original language	English
Pages (from-to)	147-50
Number of pages	96
Journal	International journal of geriatric psychiatry
Volume	21
Publication status	Published - 2006

Keywords

aged
anxiety disorders
anxiety disorders complications
autonomic nervous system
autonomic nervous system physiopathology
case control studies
chronic disease
cross sectional studies
depressive disorder
female
heart rate
heart rate physiology
hrv
humans
major
major complications
major physiopathology
male
primary health care
psychiatric status rating scales
severity illness index

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Differences in heart rate variability between depressed and non-depressed elderly.",

abstract = "OBJECTIVE: To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD: A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched for age and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. RESULTS: Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. CONCLUSION: Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.",

keywords = "aged, anxiety disorders, anxiety disorders complications, autonomic nervous system, autonomic nervous system physiopathology, case control studies, chronic disease, cross sectional studies, depressive disorder, female, heart rate, heart rate physiology, hrv, humans, major, major complications, major physiopathology, male, primary health care, psychiatric status rating scales, severity illness index",

author = "{{Van der Kooy}}, {Koen G} and {{Van Hout}}, {Hein P J} and {Van Marwijk}, Harm and {{De Haan}}, Marten and Stehouwer, {Coen D A} and Beekman, {Aartjan T F}",

year = "2006",

language = "English",

volume = "21",

pages = "147--50",

journal = "International journal of geriatric psychiatry",

issn = "1099-1166",

publisher = "John Wiley & Sons Ltd",

}

TY - JOUR

T1 - Differences in heart rate variability between depressed and non-depressed elderly.

AU - {Van der Kooy}, Koen G

AU - {Van Hout}, Hein P J

AU - Van Marwijk, Harm

AU - {De Haan}, Marten

AU - Stehouwer, Coen D A

AU - Beekman, Aartjan T F

PY - 2006

Y1 - 2006

N2 - OBJECTIVE: To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD: A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched for age and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. RESULTS: Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. CONCLUSION: Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

AB - OBJECTIVE: To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD: A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed controls (matched for age and gender) recruited in family practices in the Netherlands. Depression was determined according to the DSM-IV criteria using the PRIME-MD. HRV was measured with an electrocardiogram (ECG) during a 5-minute supine rest. RESULTS: Multivariate analyses showed statistically significant decrease in HRV in MDD patients compared with controls. CONCLUSION: Older primary care patients with MDD have a reduced HRV. This may explain why depression is a risk factor for cardiovascular disease and mortality.

KW - aged

KW - anxiety disorders

KW - anxiety disorders complications

KW - autonomic nervous system

KW - autonomic nervous system physiopathology

KW - case control studies

KW - chronic disease

KW - cross sectional studies

KW - depressive disorder

KW - female

KW - heart rate

KW - heart rate physiology

KW - hrv

KW - humans

KW - major

KW - major complications

KW - major physiopathology

KW - male

KW - primary health care

KW - psychiatric status rating scales

KW - severity illness index

M3 - Article

SN - 1099-1166

VL - 21

SP - 147

EP - 150

JO - International journal of geriatric psychiatry

JF - International journal of geriatric psychiatry

ER -

Differences in heart rate variability between depressed and non-depressed elderly.

Abstract

Keywords

UN SDGs

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