Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation

Abdullah Pandor; Daniel Horner; Sarah Davis; Steve Goodacre; John W Stevens; Mark Clowes; Beverley J Hunt; Tim Nokes; Jonathan Keenan; Kerstin de Wit

doi:10.3310/hta23630

Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation

Abdullah Pandor, Daniel Horner, Sarah Davis, Steve Goodacre, John W Stevens, Mark Clowes, Beverley J Hunt, Tim Nokes, Jonathan Keenan, Kerstin de Wit

Division of Immunology, Immunity to Infection and Respiratory Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Abstract
Background
Thromboprophylaxis can reduce the risk of venous thromboembolism (VTE) during lower-limb immobilisation, but it is unclear whether or not this translates into meaningful health benefit, justifies the risk of bleeding or is cost-effective. Risk assessment models (RAMs) could select higher-risk individuals for thromboprophylaxis.

Original language	Undefined
Journal	Health Technology Assessment
Volume	23
Issue number	63
DOIs	https://doi.org/10.3310/hta23630
Publication status	Published - 1 Dec 2019

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abstract = "AbstractBackgroundThromboprophylaxis can reduce the risk of venous thromboembolism (VTE) during lower-limb immobilisation, but it is unclear whether or not this translates into meaningful health benefit, justifies the risk of bleeding or is cost-effective. Risk assessment models (RAMs) could select higher-risk individuals for thromboprophylaxis.",

author = "Abdullah Pandor and Daniel Horner and Sarah Davis and Steve Goodacre and Stevens, {John W} and Mark Clowes and Hunt, {Beverley J} and Tim Nokes and Jonathan Keenan and Wit, {Kerstin de}",

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AU - Pandor, Abdullah

AU - Horner, Daniel

AU - Davis, Sarah

AU - Goodacre, Steve

AU - Stevens, John W

AU - Clowes, Mark

AU - Hunt, Beverley J

AU - Nokes, Tim

AU - Keenan, Jonathan

AU - Wit, Kerstin de

PY - 2019/12/1

Y1 - 2019/12/1

N2 - AbstractBackgroundThromboprophylaxis can reduce the risk of venous thromboembolism (VTE) during lower-limb immobilisation, but it is unclear whether or not this translates into meaningful health benefit, justifies the risk of bleeding or is cost-effective. Risk assessment models (RAMs) could select higher-risk individuals for thromboprophylaxis.

AB - AbstractBackgroundThromboprophylaxis can reduce the risk of venous thromboembolism (VTE) during lower-limb immobilisation, but it is unclear whether or not this translates into meaningful health benefit, justifies the risk of bleeding or is cost-effective. Risk assessment models (RAMs) could select higher-risk individuals for thromboprophylaxis.

UR - https://doi.org/10.3310/hta23630

U2 - 10.3310/hta23630

DO - 10.3310/hta23630

M3 - Article

SN - 1366-5278

VL - 23

JO - Health Technology Assessment

JF - Health Technology Assessment

IS - 63

ER -

Different strategies for pharmacological thromboprophylaxis for lower-limb immobilisation after injury: systematic review and economic evaluation

Abstract

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