Digital twins for the era of personalized surgery

Yosra Magdi Mekki; Gijs Luijten; Elisabet Hagert; Sirajeddin Belkhair; Chris Varghese; Junaid Qadir; Barry Solaiman; Muhammad Bilal; Jaghtar Dhanda; Jan Egger; Jun Deng; Vikas Khanduja; Alejandro F Frangi; Susu M Zughaier; Mitchell A Stotland

doi:10.1038/s41746-025-01575-5

Digital twins for the era of personalized surgery

Yosra Magdi Mekki, Gijs Luijten, Elisabet Hagert, Sirajeddin Belkhair, Chris Varghese, Junaid Qadir, Barry Solaiman, Muhammad Bilal, Jaghtar Dhanda, Jan Egger, Jun Deng, Vikas Khanduja, Alejandro F Frangi, Susu M Zughaier, Mitchell A Stotland

Research output: Contribution to journal › Review article › peer-review

Abstract

Digital twins can aid surgeons in training and in performing interventions with greater awareness and precision. The range and variety of digital twins in surgery are described, and their use across perioperative care is discussed. While largely experimental, they are beginning to show promise for the enhancement of personalized, adaptive, and data-driven surgical care. Issues relevant to the greater adoption and deployment of digital twins are all considered.

Original language	English
Article number	283
Journal	npj Digital Medicine
Volume	8
Issue number	1
DOIs	https://doi.org/10.1038/s41746-025-01575-5
Publication status	Published - 15 May 2025

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title = "Digital twins for the era of personalized surgery",

abstract = "Digital twins can aid surgeons in training and in performing interventions with greater awareness and precision. The range and variety of digital twins in surgery are described, and their use across perioperative care is discussed. While largely experimental, they are beginning to show promise for the enhancement of personalized, adaptive, and data-driven surgical care. Issues relevant to the greater adoption and deployment of digital twins are all considered.",

author = "Mekki, {Yosra Magdi} and Gijs Luijten and Elisabet Hagert and Sirajeddin Belkhair and Chris Varghese and Junaid Qadir and Barry Solaiman and Muhammad Bilal and Jaghtar Dhanda and Jan Egger and Jun Deng and Vikas Khanduja and Frangi, {Alejandro F} and Zughaier, {Susu M} and Stotland, {Mitchell A}",

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AU - Mekki, Yosra Magdi

AU - Luijten, Gijs

AU - Hagert, Elisabet

AU - Belkhair, Sirajeddin

AU - Varghese, Chris

AU - Qadir, Junaid

AU - Solaiman, Barry

AU - Bilal, Muhammad

AU - Dhanda, Jaghtar

AU - Egger, Jan

AU - Deng, Jun

AU - Khanduja, Vikas

AU - Frangi, Alejandro F

AU - Zughaier, Susu M

AU - Stotland, Mitchell A

PY - 2025/5/15

Y1 - 2025/5/15

N2 - Digital twins can aid surgeons in training and in performing interventions with greater awareness and precision. The range and variety of digital twins in surgery are described, and their use across perioperative care is discussed. While largely experimental, they are beginning to show promise for the enhancement of personalized, adaptive, and data-driven surgical care. Issues relevant to the greater adoption and deployment of digital twins are all considered.

AB - Digital twins can aid surgeons in training and in performing interventions with greater awareness and precision. The range and variety of digital twins in surgery are described, and their use across perioperative care is discussed. While largely experimental, they are beginning to show promise for the enhancement of personalized, adaptive, and data-driven surgical care. Issues relevant to the greater adoption and deployment of digital twins are all considered.

U2 - 10.1038/s41746-025-01575-5

DO - 10.1038/s41746-025-01575-5

M3 - Review article

C2 - 40374901

SN - 2398-6352

VL - 8

JO - npj Digital Medicine

JF - npj Digital Medicine

IS - 1

M1 - 283

ER -

Digital twins for the era of personalized surgery

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