Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells

Stuart Jones, Jonathan Ahmet, Kelly Ayton, Matthew Ball, Mark Cockerill, Emma Fairweather, Nicola Hamilton, Paul Harper, James Hitchin, Allan Jordan, Colin Levy, Ruth Lopez, Edward Mckenzie, Martin Packer, Darren Plant, Iain Simpson, Peter Simpson, Ian Sinclair, Tim C P Somervaille, Helen SmallGary J Spencer, Graeme Thomson, Michael Tonge, Ian Waddell, Jarrod Walsh, Bohdan Waszkowycz, Mark Wigglesworth, Daniel H Wiseman, Donald Ogilvie

Research output: Contribution to journal › Article › peer-review

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science