Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor

M. Raymond V Finlay^*, Mark Anderton, Susan Ashton, Peter Ballard, Paul A. Bethel, Matthew R. Box, Robert H. Bradbury, Simon J. Brown, Sam Butterworth, Andrew Campbell, Christopher Chorley, Nicola Colclough, Darren A E Cross, Gordon S. Currie, Matthew Grist, Lorraine Hassall, George B. Hill, Daniel James, Michael James, Paul KemmittTeresa Klinowska, Gillian Lamont, Scott G. Lamont, Nathaniel Martin, Heather L. McFarland, Martine J. Mellor, Jonathon P. Orme, David Perkins, Paula Perkins, Graham Richmond, Peter Smith, Richard A. Ward, Michael J. Waring, David Whittaker, Stuart Wells, Gail L. WrigleyShow 16 moreShow less