Distribution of immunoglobulin heavy chains in diseased synovia.

AJ Freemont, C. Rutley

    Research output: Contribution to journalArticlepeer-review


    Synovium from 142 patients with 12 different arthropathies was examined for the distribution of alpha, delta, gamma, and mu immunoglobulin heavy chains. A high proportion of plasma cells in the superficial subintima in all diseases reacted for alpha heavy chains. Only in rheumatoid disease did the synovium contain more than 10% of plasma cells reacting for mu heavy chains.
    Original languageEnglish
    JournalJ Clin Pathol
    Volume39( 7)
    Publication statusPublished - Jul 1986


    • immunology: Arthritis, Rheumatoid
    • Cell Count
    • Humans
    • analysis: Immunoglobulins, Heavy-Chain
    • analysis: Immunoglobulins, alpha-Chain
    • immunology: Joint Diseases
    • immunology: Plasma Cells
    • Research Support, Non-U.S. Gov't
    • immunology: Synovial Membrane


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