DNA variants in the human RAB3A gene are not associated with autism

Janine Lamb; P. D'Adamo; E. Bacchelli; F. Blasi; H. P. Lipp; D. Toniolo; E. Maestrini; Jonathan Green

doi:10.1111/j.1601-183X.2003.00058.x

DNA variants in the human RAB3A gene are not associated with autism

Janine Lamb, P. D'Adamo, E. Bacchelli, F. Blasi, H. P. Lipp, D. Toniolo, E. Maestrini, Jonathan Green

Research output: Contribution to journal › Article › peer-review

Abstract

Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.

Original language	English
Pages (from-to)	123-124
Number of pages	1
Journal	Genes, Brain and Behavior
Volume	3
Issue number	2
DOIs	https://doi.org/10.1111/j.1601-183X.2003.00058.x
Publication status	Published - Apr 2004

Keywords

ADHD
Autism
Human
Mouse
Mutation
Rab3a

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10.1111/j.1601-183X.2003.00058.x

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abstract = "Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.",

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AU - D'Adamo, P.

AU - Bacchelli, E.

AU - Blasi, F.

AU - Lipp, H. P.

AU - Toniolo, D.

AU - Maestrini, E.

AU - Green, Jonathan

PY - 2004/4

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AB - Mutation screening of the RAB3A gene in 47 individuals with autism provided no evidence that DNA variants in this gene are associated with autism. Since Rab3a constitutive knockout mice react to novel stimuli with hyperactivity, a further search for association of RAB3A DNA variants with other neurobehavioral disorders such as attention deficit/hyperactivity disorder appears justified.

KW - ADHD

KW - Autism

KW - Human

KW - Mouse

KW - Mutation

KW - Rab3a

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DO - 10.1111/j.1601-183X.2003.00058.x

M3 - Article

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JO - Genes, Brain and Behavior

JF - Genes, Brain and Behavior

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DNA variants in the human RAB3A gene are not associated with autism

Abstract

Keywords

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