Domino N- / C-arylation via in situ generation of a directing group: Atom efficient arylation using diaryliodonium salts

Christopher Teskey, Shariar Md Abu Sohel, Danielle Bunting, Sachinkumar Modha, Michael Greaney

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    Abstract

    Both aryl components of diaryliodonium salts can be used in a domino one-pot reaction via in situ generation of a directing group. A number of heterocycles undergo N-arylation which is followed by ruthenium-catalyzed C-arylation. Notably the reaction extends well to unsymmetrical diaryliodonium salts with a number of highly selective examples shown.
    Original languageEnglish
    Pages (from-to)5263–5266
    JournalAngewandte Chemie - International Edition
    Volume56
    Issue number19
    Early online date7 Apr 2017
    DOIs
    Publication statusPublished - 2017

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