Don't Fence Me In: How Cancer Cells Divide in Crowded Spaces

Nawseen Tarannum; Sarah Woolner

doi:10.1016/j.devcel.2020.02.007

Don't Fence Me In: How Cancer Cells Divide in Crowded Spaces

Research output: Contribution to journal › Editorial

Abstract

Cells in our body have to divide within a defined tissue space, which in tumors is more restricted than in normal tissue. In this issue of Developmental Cell, Matthews et al. (2020) reveal that oncogenic RasV12-mediated cell rounding and cortical stiffening promote cell division under confined conditions that are similar to those in tumors.

Original language	English
Pages (from-to)	541-542
Number of pages	2
Journal	Developmental cell
Volume	52
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2020.02.007
Publication status	Published - 9 Mar 2020

Keywords

Carcinogenesis
Cell Division
Cell Shape
Humans
Neoplasms
Signal Transduction

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.devcel.2020.02.007

Cite this

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title = "Don't Fence Me In: How Cancer Cells Divide in Crowded Spaces",

abstract = "Cells in our body have to divide within a defined tissue space, which in tumors is more restricted than in normal tissue. In this issue of Developmental Cell, Matthews et al. (2020) reveal that oncogenic RasV12-mediated cell rounding and cortical stiffening promote cell division under confined conditions that are similar to those in tumors.",

keywords = "Carcinogenesis, Cell Division, Cell Shape, Humans, Neoplasms, Signal Transduction",

author = "Nawseen Tarannum and Sarah Woolner",

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AU - Tarannum, Nawseen

AU - Woolner, Sarah

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N2 - Cells in our body have to divide within a defined tissue space, which in tumors is more restricted than in normal tissue. In this issue of Developmental Cell, Matthews et al. (2020) reveal that oncogenic RasV12-mediated cell rounding and cortical stiffening promote cell division under confined conditions that are similar to those in tumors.

AB - Cells in our body have to divide within a defined tissue space, which in tumors is more restricted than in normal tissue. In this issue of Developmental Cell, Matthews et al. (2020) reveal that oncogenic RasV12-mediated cell rounding and cortical stiffening promote cell division under confined conditions that are similar to those in tumors.

KW - Carcinogenesis

KW - Cell Division

KW - Cell Shape

KW - Humans

KW - Neoplasms

KW - Signal Transduction

U2 - 10.1016/j.devcel.2020.02.007

DO - 10.1016/j.devcel.2020.02.007

M3 - Editorial

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SN - 1534-5807

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SP - 541

EP - 542

JO - Developmental cell

JF - Developmental cell

IS - 5

ER -

Don't Fence Me In: How Cancer Cells Divide in Crowded Spaces

Abstract

Keywords

UN SDGs

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