Don't Fence Me In: How Cancer Cells Divide in Crowded Spaces

Nawseen Tarannum, Sarah Woolner

Research output: Contribution to journalEditorial


Cells in our body have to divide within a defined tissue space, which in tumors is more restricted than in normal tissue. In this issue of Developmental Cell, Matthews et al. (2020) reveal that oncogenic RasV12-mediated cell rounding and cortical stiffening promote cell division under confined conditions that are similar to those in tumors.

Original languageEnglish
Pages (from-to)541-542
Number of pages2
JournalDevelopmental cell
Issue number5
Publication statusPublished - 9 Mar 2020


  • Carcinogenesis
  • Cell Division
  • Cell Shape
  • Humans
  • Neoplasms
  • Signal Transduction


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