Dual-functional probes towards in vivo studies of brain connectivity and plasticity

Nikos Logothetis; Ilgar Mamedov; Jörn Engelmann; Oxana Eschenko; Michael Beyerlein; Nikos K. Logothetis

doi:10.1039/c1cc15991g

Dual-functional probes towards in vivo studies of brain connectivity and plasticity

Nikos Logothetis, Ilgar Mamedov, Jörn Engelmann, Oxana Eschenko, Michael Beyerlein, Nikos K. Logothetis

Research output: Contribution to journal › Article › peer-review

Abstract

A Gd 3+ based paramagnetic dextran conjugate has been developed, which enables the tracking of neuroanatomical connectivity in the brain by both MR and optical imaging. Cell studies and subsequent in vivo experiments in rodents demonstrate efficient internalisation and transport properties of the new tracer molecule. This journal is © The Royal Society of Chemistry 2012.

Original language	English
Pages (from-to)	2755-2757
Number of pages	2
Journal	Chemical Communications
Volume	48
Issue number	22
DOIs	https://doi.org/10.1039/c1cc15991g
Publication status	Published - 14 Mar 2012

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title = "Dual-functional probes towards in vivo studies of brain connectivity and plasticity",

abstract = "A Gd 3+ based paramagnetic dextran conjugate has been developed, which enables the tracking of neuroanatomical connectivity in the brain by both MR and optical imaging. Cell studies and subsequent in vivo experiments in rodents demonstrate efficient internalisation and transport properties of the new tracer molecule. This journal is {\textcopyright} The Royal Society of Chemistry 2012.",

author = "Nikos Logothetis and Ilgar Mamedov and J{\"o}rn Engelmann and Oxana Eschenko and Michael Beyerlein and Logothetis, {Nikos K.}",

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AU - Mamedov, Ilgar

AU - Engelmann, Jörn

AU - Eschenko, Oxana

AU - Beyerlein, Michael

AU - Logothetis, Nikos K.

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AB - A Gd 3+ based paramagnetic dextran conjugate has been developed, which enables the tracking of neuroanatomical connectivity in the brain by both MR and optical imaging. Cell studies and subsequent in vivo experiments in rodents demonstrate efficient internalisation and transport properties of the new tracer molecule. This journal is © The Royal Society of Chemistry 2012.

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DO - 10.1039/c1cc15991g

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JO - Chemical Communications

JF - Chemical Communications

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Dual-functional probes towards in vivo studies of brain connectivity and plasticity

Abstract

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