Projects per year
Radical control: A single glutamate residue (E287) in the coenzyme B12-dependent ethanolamine ammonia lyase is pivotal to generating high-energy radical intermediates during catalysis and then controlling the radical chemistry. Using a dynamic, electrostatic mechanism, it helps to guide the radical intermediates towards the desired end by preventing side reactions. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
|Number of pages||4|
|Journal||ChemBioChem: a European journal of chemical biology|
|Publication status||Published - Sept 2013|
- Coenzyme B12
- Protein dynamics
Research Beacons, Institutes and Platforms
- Photon Science Institute
FingerprintDive into the research topics of 'Dynamic, Electrostatic Model for the Generation and Control of High-Energy Radical Intermediates by a Coenzyme B12-Dependent Enzyme'. Together they form a unique fingerprint.
- 1 Finished
1/09/10 → 31/08/15