EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma

Enrico Franceschi; Silvia Hofer; Alba A. Brandes; Didier Frappaz; Rolf Dieter Kortmann; Jacoline Bromberg; Volodia Dangouloff-Ros; Nathalie Boddaert; Elke Hattingen; Benedikt Wiestler; Steven C. Clifford; Dominique Figarella-Branger; Felice Giangaspero; Christine Haberler; Torsten Pietsch; Kristian W. Pajtler; Stefan M. Pfister; Raphael Guzman; Walter Stummer; Stephanie E. Combs; Clemens Seidel; Dagmar Beier; Martin G. McCabe; Michael Grotzer; Florence Laigle-Donadey; Ana S.Guerreiro Stücklin; Ahmed Idbaih; Matthias Preusser; Martin van den Bent; Michael Weller; Peter Hau

doi:10.1016/S1470-2045(19)30669-2

EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma

Enrico Franceschi
, Silvia Hofer
, Alba A. Brandes
, Didier Frappaz
, Rolf Dieter Kortmann
, Jacoline Bromberg
, Volodia Dangouloff-Ros
, Nathalie Boddaert
, Elke Hattingen
, Benedikt Wiestler
, Steven C. Clifford
, Dominique Figarella-Branger
, Felice Giangaspero
, Christine Haberler
, Torsten Pietsch
, Kristian W. Pajtler
, Stefan M. Pfister
, Raphael Guzman
, Walter Stummer
, Stephanie E. Combs

Clemens Seidel, Dagmar Beier, Martin G. McCabe, Michael Grotzer, Florence Laigle-Donadey, Ana S.Guerreiro Stücklin, Ahmed Idbaih, Matthias Preusser, Martin van den Bent, Michael Weller, Peter Hau^*

^*Corresponding author for this work

Division of Cancer Sciences (L5)

Azienda USL di Bologna
IRCCS Institute of Neurological Sciences
Luzerner Kantonsspital
Centre Leon Berard
University Hospital Leipzig
Erasmus MC
IMAGINE Institute
Goethe-Universitat Frankfurt
Technische Universitat Munchen
Newcastle University
UMR 6242 CNRS
Università degli Studi di Roma La Sapienza
Istituto Neurologico Mediterraneo Neuromed
Medizinische Universitat Wien Medical University Vienna
University of Bonn Medical Center
University Hospital Heidelberg
University Hospital Münster
Helmholtz-Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH
Odense University Hospital
University Children's Hospital
AP-HP Hôpital Pitié-Salpêtrière
Universite de Paris VI (Pierre et Marie Curie)
Comprehensive Cancer Center
University of Zurich
University Hospital Regensburg
Universitätsspital Basel
University Children's Hospital Basel
UniversitatsSpital Zurich (University Hospital of Zurich)

Research output: Contribution to journal › Review article › peer-review

Abstract

The European Association of Neuro-Oncology (EANO) and EUropean RAre CANcer (EURACAN) guideline provides recommendations for the diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. The guideline is based on the 2016 WHO classification of tumours of the CNS and on scientific developments published since 1980. It aims to provide direction for diagnostic and management decisions, and for limiting unnecessary treatments and cost. In view of the scarcity of data in adults with medulloblastoma, we base our recommendations on adult data when possible, but also include recommendations derived from paediatric data if justified. Our recommendations are a resource for professionals involved in the management of post-pubertal and adult patients with medulloblastoma, for patients and caregivers, and for health-care providers in Europe. The implementation of this guideline requires multidisciplinary structures of care, and defined processes of diagnosis and treatment.

Original language	English
Pages (from-to)	e715-e728
Journal	The Lancet Oncology
Volume	20
Issue number	12
DOIs	https://doi.org/10.1016/S1470-2045(19)30669-2
Publication status	Published - 2 Dec 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Beacons, Institutes and Platforms

Manchester Cancer Research Centre

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10.1016/S1470-2045(19)30669-2

Cite this

Franceschi, E., Hofer, S., Brandes, A. A., Frappaz, D., Kortmann, R. D., Bromberg, J., Dangouloff-Ros, V., Boddaert, N., Hattingen, E., Wiestler, B., Clifford, S. C., Figarella-Branger, D., Giangaspero, F., Haberler, C., Pietsch, T., Pajtler, K. W., Pfister, S. M., Guzman, R., Stummer, W., ... Hau, P. (2019). EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. The Lancet Oncology, 20(12), e715-e728. https://doi.org/10.1016/S1470-2045(19)30669-2

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title = "EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma",

abstract = "The European Association of Neuro-Oncology (EANO) and EUropean RAre CANcer (EURACAN) guideline provides recommendations for the diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. The guideline is based on the 2016 WHO classification of tumours of the CNS and on scientific developments published since 1980. It aims to provide direction for diagnostic and management decisions, and for limiting unnecessary treatments and cost. In view of the scarcity of data in adults with medulloblastoma, we base our recommendations on adult data when possible, but also include recommendations derived from paediatric data if justified. Our recommendations are a resource for professionals involved in the management of post-pubertal and adult patients with medulloblastoma, for patients and caregivers, and for health-care providers in Europe. The implementation of this guideline requires multidisciplinary structures of care, and defined processes of diagnosis and treatment.",

author = "Enrico Franceschi and Silvia Hofer and Brandes, \{Alba A.\} and Didier Frappaz and Kortmann, \{Rolf Dieter\} and Jacoline Bromberg and Volodia Dangouloff-Ros and Nathalie Boddaert and Elke Hattingen and Benedikt Wiestler and Clifford, \{Steven C.\} and Dominique Figarella-Branger and Felice Giangaspero and Christine Haberler and Torsten Pietsch and Pajtler, \{Kristian W.\} and Pfister, \{Stefan M.\} and Raphael Guzman and Walter Stummer and Combs, \{Stephanie E.\} and Clemens Seidel and Dagmar Beier and McCabe, \{Martin G.\} and Michael Grotzer and Florence Laigle-Donadey and St{\"u}cklin, \{Ana S.Guerreiro\} and Ahmed Idbaih and Matthias Preusser and \{van den Bent\}, Martin and Michael Weller and Peter Hau",

year = "2019",

month = dec,

day = "2",

doi = "10.1016/S1470-2045(19)30669-2",

language = "English",

volume = "20",

pages = "e715--e728",

journal = "The Lancet Oncology",

issn = "1470-2045",

publisher = "Elsevier BV",

number = "12",

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Franceschi, E, Hofer, S, Brandes, AA, Frappaz, D, Kortmann, RD, Bromberg, J, Dangouloff-Ros, V, Boddaert, N, Hattingen, E, Wiestler, B, Clifford, SC, Figarella-Branger, D, Giangaspero, F, Haberler, C, Pietsch, T, Pajtler, KW, Pfister, SM, Guzman, R, Stummer, W, Combs, SE, Seidel, C, Beier, D, McCabe, MG, Grotzer, M, Laigle-Donadey, F, Stücklin, ASG, Idbaih, A, Preusser, M, van den Bent, M, Weller, M & Hau, P 2019, 'EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma', The Lancet Oncology, vol. 20, no. 12, pp. e715-e728. https://doi.org/10.1016/S1470-2045(19)30669-2

TY - JOUR

T1 - EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma

AU - Franceschi, Enrico

AU - Hofer, Silvia

AU - Brandes, Alba A.

AU - Frappaz, Didier

AU - Kortmann, Rolf Dieter

AU - Bromberg, Jacoline

AU - Dangouloff-Ros, Volodia

AU - Boddaert, Nathalie

AU - Hattingen, Elke

AU - Wiestler, Benedikt

AU - Clifford, Steven C.

AU - Figarella-Branger, Dominique

AU - Giangaspero, Felice

AU - Haberler, Christine

AU - Pietsch, Torsten

AU - Pajtler, Kristian W.

AU - Pfister, Stefan M.

AU - Guzman, Raphael

AU - Stummer, Walter

AU - Combs, Stephanie E.

AU - Seidel, Clemens

AU - Beier, Dagmar

AU - McCabe, Martin G.

AU - Grotzer, Michael

AU - Laigle-Donadey, Florence

AU - Stücklin, Ana S.Guerreiro

AU - Idbaih, Ahmed

AU - Preusser, Matthias

AU - van den Bent, Martin

AU - Weller, Michael

AU - Hau, Peter

PY - 2019/12/2

Y1 - 2019/12/2

N2 - The European Association of Neuro-Oncology (EANO) and EUropean RAre CANcer (EURACAN) guideline provides recommendations for the diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. The guideline is based on the 2016 WHO classification of tumours of the CNS and on scientific developments published since 1980. It aims to provide direction for diagnostic and management decisions, and for limiting unnecessary treatments and cost. In view of the scarcity of data in adults with medulloblastoma, we base our recommendations on adult data when possible, but also include recommendations derived from paediatric data if justified. Our recommendations are a resource for professionals involved in the management of post-pubertal and adult patients with medulloblastoma, for patients and caregivers, and for health-care providers in Europe. The implementation of this guideline requires multidisciplinary structures of care, and defined processes of diagnosis and treatment.

AB - The European Association of Neuro-Oncology (EANO) and EUropean RAre CANcer (EURACAN) guideline provides recommendations for the diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. The guideline is based on the 2016 WHO classification of tumours of the CNS and on scientific developments published since 1980. It aims to provide direction for diagnostic and management decisions, and for limiting unnecessary treatments and cost. In view of the scarcity of data in adults with medulloblastoma, we base our recommendations on adult data when possible, but also include recommendations derived from paediatric data if justified. Our recommendations are a resource for professionals involved in the management of post-pubertal and adult patients with medulloblastoma, for patients and caregivers, and for health-care providers in Europe. The implementation of this guideline requires multidisciplinary structures of care, and defined processes of diagnosis and treatment.

UR - https://www.scopus.com/pages/publications/85075720011

U2 - 10.1016/S1470-2045(19)30669-2

DO - 10.1016/S1470-2045(19)30669-2

M3 - Review article

C2 - 31797797

AN - SCOPUS:85075720011

SN - 1470-2045

VL - 20

SP - e715-e728

JO - The Lancet Oncology

JF - The Lancet Oncology

IS - 12

ER -

EANO–EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma

Abstract

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