Early aseptic loosening of cemented total hip, arthroplasty: The influence of non-steroidal anti-inflammatory drugs and smoking

Hammad Malik, M. H A Malik, J. Gray, P. R. Kay

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The purpose of this study was to investigate whether the clinical variables of non-steroidal anti-inflammatory drugs (NSAID) usage and cigarette smoking are possibly linked to aseptic loosening around total hip arthroplasty (THA). We performed a retrospective review of the records and radiographs of 224 patients attending for follow-up at Wrightington Hospital between August 2002 and 2003 who had undergone THA. The following information was recorded: age, gender, primary and revision surgery details, radiographic parameters, smoking history and NSAID usage history. Logistic regression analysis was used to determine if there is any statistically significant association between NSAID usage or smoking habit and aseptic loosening. No such association was found.
    Original languageEnglish
    Pages (from-to)211-213
    Number of pages2
    JournalInternational Orthopaedics
    Volume28
    Issue number4
    Publication statusPublished - Aug 2004

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