Early changes in thyroid-stimulating antibody activity following radioiodine therapy.

Akheel A Syed; Carol Evans; Marian Ludgate; John H Lazarus

doi:10.1159/000072296

Early changes in thyroid-stimulating antibody activity following radioiodine therapy.

Akheel A Syed, Carol Evans, Marian Ludgate, John H Lazarus

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS: Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 with TMNG) at a median 0.5 months before and 3 months after (131)I treatment using a standard ablative dose of 555 MBq. TRAb-S activity was measured in a sensitive and specific luminescent bioassay employing the lulu cell line and expressed as a stimulation index (SI; normal

Original language	English
Journal	Medical principles and practice : international journal of the Kuwait University, Health Science Centre
Volume	12
Issue number	4
DOIs	https://doi.org/10.1159/000072296
Publication status	Published - Sept 2003
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000072296

Cite this

@article{f1648d3c21ce4af88217ad48f69ce180,

title = "Early changes in thyroid-stimulating antibody activity following radioiodine therapy.",

abstract = "OBJECTIVE: The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS: Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 with TMNG) at a median 0.5 months before and 3 months after (131)I treatment using a standard ablative dose of 555 MBq. TRAb-S activity was measured in a sensitive and specific luminescent bioassay employing the lulu cell line and expressed as a stimulation index (SI; normal",

author = "Syed, {Akheel A} and Carol Evans and Marian Ludgate and Lazarus, {John H}",

year = "2003",

month = sep,

doi = "10.1159/000072296",

language = "English",

volume = "12",

journal = "Medical principles and practice : international journal of the Kuwait University, Health Science Centre",

issn = "1011-7571",

publisher = "S. Karger AG",

number = "4",

}

TY - JOUR

T1 - Early changes in thyroid-stimulating antibody activity following radioiodine therapy.

AU - Syed, Akheel A

AU - Evans, Carol

AU - Ludgate, Marian

AU - Lazarus, John H

PY - 2003/9

Y1 - 2003/9

N2 - OBJECTIVE: The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS: Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 with TMNG) at a median 0.5 months before and 3 months after (131)I treatment using a standard ablative dose of 555 MBq. TRAb-S activity was measured in a sensitive and specific luminescent bioassay employing the lulu cell line and expressed as a stimulation index (SI; normal

AB - OBJECTIVE: The aim of this study was to determine whether or not the titre of thyroid-stimulating hormone receptor antibody with stimulating (TRAb-S) activity changes in patients with Graves' disease (GD) or toxic multinodular goitres (TMNG) 3 months after treatment with sodium iodide ((131)I). SUBJECTS AND METHODS: Serum specimens were obtained from 21 hyperthyroid patients (15 with GD and 6 with TMNG) at a median 0.5 months before and 3 months after (131)I treatment using a standard ablative dose of 555 MBq. TRAb-S activity was measured in a sensitive and specific luminescent bioassay employing the lulu cell line and expressed as a stimulation index (SI; normal

U2 - 10.1159/000072296

DO - 10.1159/000072296

M3 - Article

C2 - 12966202

SN - 1011-7571

VL - 12

JO - Medical principles and practice : international journal of the Kuwait University, Health Science Centre

JF - Medical principles and practice : international journal of the Kuwait University, Health Science Centre

IS - 4

ER -

Early changes in thyroid-stimulating antibody activity following radioiodine therapy.

Abstract

UN SDGs

Access to Document

Fingerprint

Cite this