Early-onset idiopathic pyoderma gangrenosum

Deepika  Roshith; Christopher  Rawlingson; Timothy H.  Clayton; Chitra  Sethuraman; Peter Arkwright

doi:10.1002/jvc2.399

Early-onset idiopathic pyoderma gangrenosum

Deepika Roshith, Christopher Rawlingson, Timothy H. Clayton, Chitra Sethuraman, Peter Arkwright

Division of Immunology, Immunity to Infection and Respiratory Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Neutrophilic dermatoses are autoinflammatory disorders characterized by sterile cutaneous inflammatory neutrophilic infiltrates. This group of diseases is rare in infants and children, where sepsis is the diagnosis of exclusion. This report focuses on the clinical presentation, investigation, and management of infants with idiopathic pyoderma gangrenosum. It should allow for a better appreciation of the disease and a more patient focused approach to its diagnosis and management.

Original language	English
Journal	JEADV Clinical Practice
Early online date	10 Mar 2024
DOIs	https://doi.org/10.1002/jvc2.399
Publication status	E-pub ahead of print - 10 Mar 2024

Keywords

neutrophilic dermatosis
pyoderma gangrenosum
Sweet syndrome
corticosteroids
dapsone
biologics

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10.1002/jvc2.399Licence: CC BY-NC-ND

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title = "Early-onset idiopathic pyoderma gangrenosum",

abstract = "Neutrophilic dermatoses are autoinflammatory disorders characterized by sterile cutaneous inflammatory neutrophilic infiltrates. This group of diseases is rare in infants and children, where sepsis is the diagnosis of exclusion. This report focuses on the clinical presentation, investigation, and management of infants with idiopathic pyoderma gangrenosum. It should allow for a better appreciation of the disease and a more patient focused approach to its diagnosis and management.",

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AU - Rawlingson, Christopher

AU - Clayton, Timothy H.

AU - Sethuraman, Chitra

AU - Arkwright, Peter

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AB - Neutrophilic dermatoses are autoinflammatory disorders characterized by sterile cutaneous inflammatory neutrophilic infiltrates. This group of diseases is rare in infants and children, where sepsis is the diagnosis of exclusion. This report focuses on the clinical presentation, investigation, and management of infants with idiopathic pyoderma gangrenosum. It should allow for a better appreciation of the disease and a more patient focused approach to its diagnosis and management.

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KW - pyoderma gangrenosum

KW - Sweet syndrome

KW - corticosteroids

KW - dapsone

KW - biologics

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Early-onset idiopathic pyoderma gangrenosum

Abstract

Keywords

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