Forty-four subjects with normal hearing wore an earplug in one ear for either 4 (n = 27) or 7 days (n= 17). Thirty subjects reported tinnitus at the end of the deprivation period. ARTs were measured before the earplug period and immediately after taking the earplug out. At the end of the earplug period, ARTs in the plugged ear were decreased by 5.9 ± 1.1 dB in the tinnitus-positive group, and by 6.3 ± 1.1 dB in the tinnitus-negative group. In the control ear, ARTs were increased by 1.3 ± 0.8 dB in the tinnitus-positive group, and by 1.6 ± 2.0 dB in the tinnitus-negative group. There were no significant differences between the groups with 4 and 7 days of auditory deprivation.
Our results suggest that either the subcortical neurophysiological changes underlying the ART reductions might not be related to the occurrence of tinnitus, or that they might be a necessary component of the generation of tinnitus, but with additional changes at a higher level of auditory processing required to give rise to tinnitus.
|Early online date||16 Mar 2019|
|Publication status||Published - 2019|
- auditory deprivation
- acoustic reflex threshold
- neural plasticity
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Munro, K., Millman, R., Lamb, W., Dawes, P., Plack, C., Stone, M., Kluk-De Kort, K., Moore, D., Morton, C., Prendergast, G., Couth, S., Schlittenlacher, J., Chilton, H., Visram, A., Dillon, H., Guest, H., Heinrich, A., Jackson, I., Littlejohn, J., Jones, L., Lough, M., Morgan, R., Perugia, E., Roughley, A., Whiston, H., Wright, C., Saunders, G., Kelly, C., Cross, H., Loughran, M. & Hoseinabadi, R.