Ectopic Cushing's syndrome secondary to olfactory neuroblastoma

K Yu , Federico Roncaroli, T Kearney , D Ewins , D Beeharry , T Naylor , D Ray , R Bhalla , K Gnanalingham

Research output: Contribution to journalArticlepeer-review


We present the case of a patient with Cushing’s syndrome secondary to ectopic ACTH secretion. A MR of the head showed a left-sided nasal mass extending down from the cribriform plate. The patient underwent endoscopic resection with nearly complete removal of the mass. Histological examination showed an ACTH-secreting olfactory neuroblastoma (ONB). The patient’s cortisol levels returned to normal range after surgery and have remained normal for over a year. ONB is a rare cause for ectopic ACTH secretion. This case highlights the diagnostic and management difficulties in patients with ectopic ACTH secretion, and provides a brief review of ONB.
Original languageEnglish
JournalActa Neurochirurgica
Publication statusPublished - 17 Jan 2018


  • Pituitary adenoma
  • Cushing's syndrome
  • Ectopic


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