Effect of electrolyte on the surface and thermodynamic properties of amphiphilic penicillins

Pablo Taboada, David Attwood, Juan M. Ruso, Manuel García, Félix Sarmiento, Víctor Mosquera

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Critical micelle concentrations and surface properties of the penicillins cloxacillin, dicloxacillin, and nafcillin in aqueous solution at 303 K and at electrolyte concentrations over the range 0.0-0.4 mol dm-3 were determined by surface tension measurements. A mass action model, modified for application to associating systems of low aggregation number, was used to calculate the standard Gibbs energy of micellization of these drugs at each electrolyte concentration.
    Original languageEnglish
    Pages (from-to)288-292
    Number of pages4
    JournalJournal of Colloid and Interface Science
    Volume220
    Issue number2
    DOIs
    Publication statusPublished - 15 Dec 1999

    Keywords

    • Free energy of micellization
    • Micellization
    • Penicillins
    • Surface activity

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