Effect of growth substrate and electron donor on hydrogenation of carbon-carbon double bonds by Acetobacterium woodii

Gillian Stephens, E. Timothy Davies, Gillian M. Stephens

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Acetobacterium woodii was grown on fructose, methanol, 3,4,5-trimethoxycinnamate, or 3-(3,4,5-trimethoxyphenyl)-propanoate in the prescence or abscence of caffeate. The cells were harvested and tested for their ability to hydrogenate C=C bonds using caffeate as a model substrate. Except for cells grown on methanol, the growth substrate was a poor electron donor for the biotransformation. 3-(3,4,55-Trimethoxyphenyl)-propanoate was the best donor for fructose-grown cells while fructose was the best donor for cells grown on methoxy-substituted aromatics. Caffeate reductase activity was inducible by caffeate or trimethoxycinnamate. The highest rates of caffeate reduction were obtained using cells which had been grown on 3,4,5-trimethoxycinnamate plus caffeate and by providing fructose as an electron donor.
    Original languageEnglish
    Pages (from-to)129-132
    Number of pages3
    JournalEnzyme and Microbial Technology
    Volume23
    Issue number1-2
    Publication statusPublished - Jul 1998

    Keywords

    • Hydrogenation (biol.
    • effect of growth substrate and electron donor on hydrogenation of carbon-carbon double bonds by Acetobacterium woodii)
    • Acetobacterium woodii
    • Double bond
    • Electron donors (effect of growth substrate and electron donor on hydrogenation of carbon-carbon double bonds by Acetobacterium woodii)
    • Acetobacterium carbon double bond hydrogenation trimethoxyphenylpropanoate

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