Effect of moderate intraocular pressure changes on topographic measurements with confocal scanning laser tomography in patients with glaucoma

Marcelo T. Nicolela, Adael S. Soares, Monica M. Carrillo, Balwantray C. Chauhan, Raymond P. LeBlanc, Paul H. Artes

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective: To evaluate optic disc topography changes after intraocular pressure (IOP) modulation in patients with glaucoma. Methods: Twenty-three patients with glaucoma were studied. Three mean optic disc topography images were obtained with the Heidelberg Retina Tomograph II at baseline and weeks 1, 2, 4, and 8 (visits 1, 2, 3, 4, and 5, respectively). Topical medications were discontinued in the study eye after visit 1 and resumed after visit 4 but maintained in the contralateral control eye. Central corneal thickness was measured at the last visit. Topographic changes were determined by stereometric parameters (rim area and mean cup depth) and at discrete topographic locations using the Topographic Change Analysis program (from the Heidelberg Retina Tomograph II). Results: In the study eyes, IOP increased significantly (5.4 mm Hg at visit 4; P
    Original languageEnglish
    Pages (from-to)633-640
    Number of pages7
    JournalArchives of Ophthalmology
    Volume124
    Issue number5
    DOIs
    Publication statusPublished - May 2006

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