Effect of PCI on quality of life in patients with stable coronary disease

William S. Weintraub, John A. Spertus, Paul Kolm, David J. Maron, Zefeng Zhang, Claudine Jurkovitz, Wei Zhang, Pamela M. Hartigan, Cheryl Lewis, Emir Veledar, Jim Bowen, Sandra B. Dunbar, Christi Deaton, Stanley Kaufman, Robert A. O'Rourke, Ron Goeree, Paul G. Barnett, Koon K. Teo, William E. Boden

    Research output: Contribution to journalArticlepeer-review


    BACKGROUND: It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS: We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS: At baseline, 22% of the patients were free of angina. At 3 months, 53% of the patients in the PCI group and 42% in the medical-therapy group were angina-free (P
    Original languageEnglish
    Pages (from-to)677-687
    Number of pages10
    JournalNew England Journal Of Medicine
    Issue number7
    Publication statusPublished - 14 Aug 2008


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