Effect of PCI on quality of life in patients with stable coronary disease

William S. Weintraub; John A. Spertus; Paul Kolm; David J. Maron; Zefeng Zhang; Claudine Jurkovitz; Wei Zhang; Pamela M. Hartigan; Cheryl Lewis; Emir Veledar; Jim Bowen; Sandra B. Dunbar; Christi Deaton; Stanley Kaufman; Robert A. O'Rourke; Ron Goeree; Paul G. Barnett; Koon K. Teo; William E. Boden

doi:10.1056/NEJMoa072771

Effect of PCI on quality of life in patients with stable coronary disease

William S. Weintraub, John A. Spertus, Paul Kolm, David J. Maron, Zefeng Zhang, Claudine Jurkovitz, Wei Zhang, Pamela M. Hartigan, Cheryl Lewis, Emir Veledar, Jim Bowen, Sandra B. Dunbar, Christi Deaton, Stanley Kaufman, Robert A. O'Rourke, Ron Goeree, Paul G. Barnett, Koon K. Teo, William E. Boden

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS: We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS: At baseline, 22% of the patients were free of angina. At 3 months, 53% of the patients in the PCI group and 42% in the medical-therapy group were angina-free (P

Original language	English
Pages (from-to)	677-687
Number of pages	10
Journal	New England Journal Of Medicine
Volume	359
Issue number	7
DOIs	https://doi.org/10.1056/NEJMoa072771
Publication status	Published - 14 Aug 2008

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http://content.nejm.org/cgi/reprint/359/7/677.pdf

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Weintraub, W. S., Spertus, J. A., Kolm, P., Maron, D. J., Zhang, Z., Jurkovitz, C., Zhang, W., Hartigan, P. M., Lewis, C., Veledar, E., Bowen, J., Dunbar, S. B., Deaton, C., Kaufman, S., O'Rourke, R. A., Goeree, R., Barnett, P. G., Teo, K. K., & Boden, W. E. (2008). Effect of PCI on quality of life in patients with stable coronary disease. New England Journal Of Medicine, 359(7), 677-687. https://doi.org/10.1056/NEJMoa072771

@article{edbeeae4809940ddafb54fb516b3f458,

title = "Effect of PCI on quality of life in patients with stable coronary disease",

abstract = "BACKGROUND: It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS: We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS: At baseline, 22\% of the patients were free of angina. At 3 months, 53\% of the patients in the PCI group and 42\% in the medical-therapy group were angina-free (P",

author = "Weintraub, \{William S.\} and Spertus, \{John A.\} and Paul Kolm and Maron, \{David J.\} and Zefeng Zhang and Claudine Jurkovitz and Wei Zhang and Hartigan, \{Pamela M.\} and Cheryl Lewis and Emir Veledar and Jim Bowen and Dunbar, \{Sandra B.\} and Christi Deaton and Stanley Kaufman and O'Rourke, \{Robert A.\} and Ron Goeree and Barnett, \{Paul G.\} and Teo, \{Koon K.\} and Boden, \{William E.\}",

year = "2008",

month = aug,

day = "14",

doi = "10.1056/NEJMoa072771",

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journal = "New England Journal Of Medicine",

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Weintraub, WS, Spertus, JA, Kolm, P, Maron, DJ, Zhang, Z, Jurkovitz, C, Zhang, W, Hartigan, PM, Lewis, C, Veledar, E, Bowen, J, Dunbar, SB, Deaton, C, Kaufman, S, O'Rourke, RA, Goeree, R, Barnett, PG, Teo, KK & Boden, WE 2008, 'Effect of PCI on quality of life in patients with stable coronary disease', New England Journal Of Medicine, vol. 359, no. 7, pp. 677-687. https://doi.org/10.1056/NEJMoa072771

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T1 - Effect of PCI on quality of life in patients with stable coronary disease

AU - Weintraub, William S.

AU - Spertus, John A.

AU - Kolm, Paul

AU - Maron, David J.

AU - Zhang, Zefeng

AU - Jurkovitz, Claudine

AU - Zhang, Wei

AU - Hartigan, Pamela M.

AU - Lewis, Cheryl

AU - Veledar, Emir

AU - Bowen, Jim

AU - Dunbar, Sandra B.

AU - Deaton, Christi

AU - Kaufman, Stanley

AU - O'Rourke, Robert A.

AU - Goeree, Ron

AU - Barnett, Paul G.

AU - Teo, Koon K.

AU - Boden, William E.

PY - 2008/8/14

Y1 - 2008/8/14

N2 - BACKGROUND: It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS: We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS: At baseline, 22% of the patients were free of angina. At 3 months, 53% of the patients in the PCI group and 42% in the medical-therapy group were angina-free (P

AB - BACKGROUND: It has not been clearly established whether percutaneous coronary intervention (PCI) can provide an incremental benefit in quality of life over that provided by optimal medical therapy among patients with chronic coronary artery disease. METHODS: We randomly assigned 2287 patients with stable coronary disease to PCI plus optimal medical therapy or to optimal medical therapy alone. We assessed angina-specific health status (with the use of the Seattle Angina Questionnaire) and overall physical and mental function (with the use of the RAND 36-item health survey [RAND-36]). RESULTS: At baseline, 22% of the patients were free of angina. At 3 months, 53% of the patients in the PCI group and 42% in the medical-therapy group were angina-free (P

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DO - 10.1056/NEJMoa072771

M3 - Article

SN - 1533-4406

VL - 359

SP - 677

EP - 687

JO - New England Journal Of Medicine

JF - New England Journal Of Medicine

IS - 7

ER -

Effect of PCI on quality of life in patients with stable coronary disease

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