Effects of 4-aminopyridine in patients with multiple sclerosis

Richard E. Jones; James R. Heron; David H. Foster; Rosemary S. Snelgar; Robert J. Mason

Effects of 4-aminopyridine in patients with multiple sclerosis

Richard E. Jones, James R. Heron, David H. Foster, Rosemary S. Snelgar, Robert J. Mason

Research output: Contribution to journal › Article › peer-review

Abstract

4-Aminopyridine (4-AP) was administered to two groups of patients with multiple sclerosis (MS). The first group consisted of 5 patients with labile visual symptoms, 2 of whom had arcuate scotomata. 4-AP improved visual performance of most patients in this group and reduced the size of scotomata. The second group consisted of 5 patients with the spinal form of MS who were in a stable state; in this group 4-AP had little effect clinically or on tests of visual function. © 1983.

Original language	English
Pages (from-to)	353-362
Number of pages	9
Journal	JOURNAL OF THE NEUROLOGICAL SCIENCES
Volume	60
Issue number	3
Publication status	Published - Aug 1983

Keywords

4-Aminopyridine
Conduction factors
Multiple Sclerosis
Psychophysical measurement

Cite this

@article{9ef84005f0a54c8fa4c86a76f6fa703a,

title = "Effects of 4-aminopyridine in patients with multiple sclerosis",

abstract = "4-Aminopyridine (4-AP) was administered to two groups of patients with multiple sclerosis (MS). The first group consisted of 5 patients with labile visual symptoms, 2 of whom had arcuate scotomata. 4-AP improved visual performance of most patients in this group and reduced the size of scotomata. The second group consisted of 5 patients with the spinal form of MS who were in a stable state; in this group 4-AP had little effect clinically or on tests of visual function. {\textcopyright} 1983.",

keywords = "4-Aminopyridine, Conduction factors, Multiple Sclerosis, Psychophysical measurement",

author = "Jones, \{Richard E.\} and Heron, \{James R.\} and Foster, \{David H.\} and Snelgar, \{Rosemary S.\} and Mason, \{Robert J.\}",

year = "1983",

month = aug,

language = "English",

volume = "60",

pages = "353--362",

journal = "JOURNAL OF THE NEUROLOGICAL SCIENCES",

issn = "1878-5883",

publisher = "Elsevier BV",

number = "3",

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TY - JOUR

T1 - Effects of 4-aminopyridine in patients with multiple sclerosis

AU - Jones, Richard E.

AU - Heron, James R.

AU - Foster, David H.

AU - Snelgar, Rosemary S.

AU - Mason, Robert J.

PY - 1983/8

Y1 - 1983/8

N2 - 4-Aminopyridine (4-AP) was administered to two groups of patients with multiple sclerosis (MS). The first group consisted of 5 patients with labile visual symptoms, 2 of whom had arcuate scotomata. 4-AP improved visual performance of most patients in this group and reduced the size of scotomata. The second group consisted of 5 patients with the spinal form of MS who were in a stable state; in this group 4-AP had little effect clinically or on tests of visual function. © 1983.

AB - 4-Aminopyridine (4-AP) was administered to two groups of patients with multiple sclerosis (MS). The first group consisted of 5 patients with labile visual symptoms, 2 of whom had arcuate scotomata. 4-AP improved visual performance of most patients in this group and reduced the size of scotomata. The second group consisted of 5 patients with the spinal form of MS who were in a stable state; in this group 4-AP had little effect clinically or on tests of visual function. © 1983.

KW - 4-Aminopyridine

KW - Conduction factors

KW - Multiple Sclerosis

KW - Psychophysical measurement

UR - https://www.scopus.com/pages/publications/0020508919

M3 - Article

SN - 1878-5883

VL - 60

SP - 353

EP - 362

JO - JOURNAL OF THE NEUROLOGICAL SCIENCES

JF - JOURNAL OF THE NEUROLOGICAL SCIENCES

IS - 3

ER -

Effects of 4-aminopyridine in patients with multiple sclerosis

Abstract

Keywords

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