Effects of adrenalectomy on energy balance, diet-induced thermogenesis and brown adipose tissue in adult cafeteria-fed rats

N. J. Rothwell, M. J. Stock, D. A. York

Research output: Contribution to journalArticlepeer-review

Abstract

1. 1. Feeding adult male rats a palatable cafeteria diet stimulated energy intake and expenditure but also raised body weight and energy gains. 2. 2. Bilateral adrenalectomy (ADX) had little effect on stock-fed animals, but prevented the development of obesity in cafeteria-fed rats by depressing food intake and energetic efficiency. 3. 3. Adrenalectomy also markedly increased the thermogenic activity of brown adipose tissue, and depressed insulin levels, particularly in the cafeteria group. © 1984.
Original languageEnglish
Pages (from-to)565-569
Number of pages4
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume78
Issue number3
Publication statusPublished - 1984

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