Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

Gina L.j. Galli; Mitchell C. Lock; Kerri L.m. Smith; Dino A. Giussani; Dane A. Crossley

doi:10.1152/physiol.00022.2022

Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

Gina L.j. Galli, Mitchell C. Lock, Kerri L.m. Smith, Dino A. Giussani, Dane A. Crossley

Research output: Contribution to journal › Review article › peer-review

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Abstract

Developmental hypoxia has profound and persistent effects on the vertebrate cardiovascular system, but the nature, magnitude and long-term outcome of the hypoxic consequences are species-specific. Here we aim to identify common and novel cardiovascular responses among vertebrates that encounter developmental hypoxia, and we discuss the possible medical and ecological implications.

Original language	English
Pages (from-to)	53-62
Journal	Physiology
Volume	38
Issue number	2
Early online date	1 Nov 2022
DOIs	https://doi.org/10.1152/physiol.00022.2022
Publication status	Published - 1 Mar 2023

Keywords

embryo
fetus
heart
hypoxia
programming

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10.1152/physiol.00022.2022

Physiology programming Review Galli et al. 2022 revised FINAL clean copy after proofsAccepted author manuscript, 242 KB

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Effects of Developmental Hypoxia on the Vertebrate Cardiovascular System

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