Abstract
The hyperthermic response to pyrogen was not potentiated by caffeine or theophylline administered i.p. into cats or rabbit. Injection of these drugs into the anterior hypothalamus or into the third cerebral ventricle in cats was also without effect on pyrexia. These results support the hypothesis that cyclic AMP in the anterior hypothalamus does not mediate pyrogen induced hyperthermia in cats.
| Original language | English |
|---|---|
| Pages (from-to) | 389-392 |
| Number of pages | 3 |
| Journal | European journal of pharmacology |
| Volume | 45 |
| Issue number | 4 |
| Publication status | Published - 1977 |