Effects of Polypropylene Glycol 400 (PPG400) on the Micellization and Gelation of Pluronic F127

Carolina Moura de Lima, Sônia M. C. Siqueira, Antonia F. V. de Amorim, Kamilla B. S. Costa, Débora H. A. de Brito, Maria E. N. P. Ribeiro, Nadja M. P. S. Ricardo, Chiraphon Chaibunditc, Stephen G. Yeates, Nágila M. P. S. Ricardo

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In dilute aqueous solution unimers of Pluronic F127 associate to form micelles. In more concentrated solution, micelles pack to form high-modulus gels. Our interest is the effect of addition of 10 to 30 wt% low molecular weight PPG400 on the micellization and gelation of solutions of F127. DLS was used to determine the apparent size of the micelles (rh,app)¬¬. The critical micelle concentration (cmc) using the dye solubilization method of F127 in PPG400 solutions was studied. It was carried out visual observation of mobility to detect gel formation in concentrated solutions and the onset of clouding and turbidity, as the temperature was raised. Oscillatory rheometry was used to confirm the formation of high-modulus gels and provide values of elastic moduli (G'max) over a wide temperature range. SAXS was used to determine gel structure. Our results for the hydrophobic adduct PPG400 were compared with literature values for the hydrophilic adduct PEG6000.
    Original languageEnglish
    Pages (from-to)7978-7982
    Number of pages4
    JournalMacromolecules
    Volume48
    Issue number21
    DOIs
    Publication statusPublished - 2015

    Keywords

    • F127, polypropylene glycol, micelle, gel, modulus

    Fingerprint

    Dive into the research topics of 'Effects of Polypropylene Glycol 400 (PPG400) on the Micellization and Gelation of Pluronic F127'. Together they form a unique fingerprint.

    Cite this