Efficient Self-Assembly of Archaeoglobus fulgidus ferritin around metallic cores

Joe Swift, Christopher A. Butts, Jasmina Cheung-Lau, Vijay Yerubandi, Ivan J. Dmochowski

    Research output: Contribution to journalArticlepeer-review


    Interfacing biological systems with inorganic nanoparticles is of great interest, as it offers means of particle stabilization and spatial control in electronic or biomedical applications. We report on the particle-directed assembly of hyperthermophile Archaeoglobus fulgidus ferritin subunits around negatively charged colloidal gold. An annealing process allows rapid assembly of the protein in near-native stoichiometry. Transmission electron microscopy suggests that greater than 95% of nanoparticles are encapsulated while the self-assembly process ensures that almost 100% of the assembled ferritin cavities are occupied. © 2009 American Chemical Society.
    Original languageEnglish
    Pages (from-to)5219-5225
    Number of pages6
    Issue number9
    Publication statusPublished - 5 May 2009


    Dive into the research topics of 'Efficient Self-Assembly of Archaeoglobus fulgidus ferritin around metallic cores'. Together they form a unique fingerprint.

    Cite this