Abstract
Interfacing biological systems with inorganic nanoparticles is of great interest, as it offers means of particle stabilization and spatial control in electronic or biomedical applications. We report on the particle-directed assembly of hyperthermophile Archaeoglobus fulgidus ferritin subunits around negatively charged colloidal gold. An annealing process allows rapid assembly of the protein in near-native stoichiometry. Transmission electron microscopy suggests that greater than 95% of nanoparticles are encapsulated while the self-assembly process ensures that almost 100% of the assembled ferritin cavities are occupied. © 2009 American Chemical Society.
| Original language | English |
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| Pages (from-to) | 5219-5225 |
| Number of pages | 6 |
| Journal | Langmuir |
| Volume | 25 |
| Issue number | 9 |
| Publication status | Published - 5 May 2009 |