Eicosanoids in skin inflammation

Anna Nicolaou

doi:10.1016/j.plefa.2012.03.009

Eicosanoids in skin inflammation

Research output: Contribution to journal › Article › peer-review

Abstract

Eicosanoids play an integral part in homeostatic mechanisms related to skin health and structural integrity. They also mediate inflammatory events developed in response to environmental factors, such as exposure to ultraviolet radiation, and inflammatory and allergic disorders, including psoriasis and atopic dermatitis. This review article discusses biochemical aspects related to cutaneous eicosanoid metabolism, the contribution of these potent autacoids to skin inflammation and related conditions, and considers the importance of nutritional supplementation with bioactives such as omega-3 and omega-6 polyunsaturated fatty acids and plant-derived antioxidants as means of addressing skin health issues. © 2012 Elsevier Ltd.

Original language	English
Pages (from-to)	131-138
Number of pages	7
Journal	Prostaglandins, Leukotrienes & Essential Fatty Acids
Volume	88
Issue number	1
DOIs	https://doi.org/10.1016/j.plefa.2012.03.009
Publication status	Published - Jan 2013

Keywords

Eicosanoids
Inflammation
Polyunsaturated fatty acids
Skin

Access to Document

10.1016/j.plefa.2012.03.009

The Effect of Dietry Bioactive Compounds on Skin Health in Humans in Vivo.
Rhodes, L. (PI) & Watson, R. (CoI)
1/09/08 → 31/08/12
Project: Research

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keywords = "Eicosanoids, Inflammation, Polyunsaturated fatty acids, Skin",

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AB - Eicosanoids play an integral part in homeostatic mechanisms related to skin health and structural integrity. They also mediate inflammatory events developed in response to environmental factors, such as exposure to ultraviolet radiation, and inflammatory and allergic disorders, including psoriasis and atopic dermatitis. This review article discusses biochemical aspects related to cutaneous eicosanoid metabolism, the contribution of these potent autacoids to skin inflammation and related conditions, and considers the importance of nutritional supplementation with bioactives such as omega-3 and omega-6 polyunsaturated fatty acids and plant-derived antioxidants as means of addressing skin health issues. © 2012 Elsevier Ltd.

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KW - Inflammation

KW - Polyunsaturated fatty acids

KW - Skin

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IS - 1

ER -

Eicosanoids in skin inflammation

Abstract

Keywords

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The Effect of Dietry Bioactive Compounds on Skin Health in Humans in Vivo.

Cite this