Electrochemical quantification of high-affinity halide binding by a steroid-based receptor

The quantification of the strength of binding between cholapod receptor and halide anions using voltammetry at the liquid/liquid interface was discussed. It was observed that quantification of binding can be achieved by analysis of the dependence of the voltammetric half-wave potential. The silver salt appropriate to the halide was employed as the aqueous phase reference electrode. The transfer potentials of fluoride, chloride and bromide from water to DCE were determined to be -0.598 V, -0.529 V and -0.446 V respectively.