Electrophoretic deposition of chitosan-based composite coatings for biomedical applications: A review

Egemen Avcu, Fatih E. Baştan, Hasan Z. Abdullah, Muhammad Atiq Ur Rehman, Yasemin Yıldıran Avcu, Aldo R. Boccaccini

Research output: Contribution to journalReview articlepeer-review


Chitosan is one of the most widely used natural biopolymers for a great variety of biomedical applications owing to its biocompatibility, biodegradability, and antibacterial activity, being generally regarded as a safe material. It can be employed as a dispersant, binder, and surface charge agent for particles in suspension. Electrophoretic deposition (EPD) of chitosan, especially in combination with other materials, is receiving increasing attention for biomedical applications. This article presents a comprehensive review of the field of EPD of chitosan-based composite coatings by highlighting their microstructural, mechanical, surface, and biological properties. Since suspension characteristics have significant influences on the deposition mechanisms, kinetics, and on the overall properties of the electrophoretically deposited coatings, suspension parameters such as concentration, viscosity, and zeta potential are discussed, including chitosan-based suspensions with hydroxyapatite, bioactive glass particles, carbonaceous materials and other inorganic and organic materials. The deposition mechanisms proposed for each composite system are highlighted. Moreover, the effects of key EPD process parameters on the microstructural homogeneity, mechanical properties as well as surface and biological characteristics of the coatings are emphasised, and specific approaches for future research are proposed based on the state-of-the-art and considering EPD produced chitosan-based coatings in applications such as tissue engineering and drug delivery systems.

Original languageEnglish
Pages (from-to)69-108
Number of pages40
JournalProgress In Materials Science
Early online date31 Jan 2019
Publication statusPublished - 1 Jun 2019


  • Biomaterials
  • Carbon nanotubes
  • Chitosan
  • Coatings
  • Electrophoretic deposition
  • Gelatin
  • Graphene oxide
  • Hydroxyapatite


Dive into the research topics of 'Electrophoretic deposition of chitosan-based composite coatings for biomedical applications: A review'. Together they form a unique fingerprint.

Cite this