Embryo morphology as a predictor of IVF success: An evaluation of the proposed UK ACE grading scheme for cleavage stage embryos

Christos Stylianou; Diane Critchlow; Daniel R. Brison; Stephen A. Roberts

doi:10.3109/14647273.2011.652251

Embryo morphology as a predictor of IVF success: An evaluation of the proposed UK ACE grading scheme for cleavage stage embryos

Christos Stylianou, Diane Critchlow, Daniel R. Brison, Stephen A. Roberts

Research output: Contribution to journal › Article › peer-review

Abstract

This study aims to provide a first evaluation of the morphological embryo grading scheme proposed in the British Fertility Society and Association of Clinical Embryologist joint guidelines for elective single embryo transfer. Pregnancy data were obtained from a cohort of patients treated at St. Mary's Hospital in Manchester, UK, between April 2007 and July 2009. Embryo morphology was assessed on day 2 or 3 prior to transfer in terms of 3 parameters: cell number, fragmentation and evenness. Cell number was parameterised as a growth rate (doublings/day). An embryo-uterus model with adjustment for other prognostic factors was used to determine the role of the three components as predictors of pregnancy. Embryo growth rate (p

Original language	English
Pages (from-to)	11-17
Number of pages	6
Journal	Human Fertility
Volume	15
Issue number	1
DOIs	https://doi.org/10.3109/14647273.2011.652251
Publication status	Published - Mar 2012

Keywords

Embryo grading
Embryo morphology
IVF
Pregnancy

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10.3109/14647273.2011.652251

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abstract = "This study aims to provide a first evaluation of the morphological embryo grading scheme proposed in the British Fertility Society and Association of Clinical Embryologist joint guidelines for elective single embryo transfer. Pregnancy data were obtained from a cohort of patients treated at St. Mary's Hospital in Manchester, UK, between April 2007 and July 2009. Embryo morphology was assessed on day 2 or 3 prior to transfer in terms of 3 parameters: cell number, fragmentation and evenness. Cell number was parameterised as a growth rate (doublings/day). An embryo-uterus model with adjustment for other prognostic factors was used to determine the role of the three components as predictors of pregnancy. Embryo growth rate (p",

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note = "HR: rejected - appealing Resub to Hum Fert 22/8/11 accepted with minor ammendments 16/11/11 proofs 13/1/12 March 2012 First ever Impact Factor now released 1.377 Read More: http://informahealthcare.com/loi/huf",

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AU - Roberts, Stephen A.

N1 - HR: rejected - appealing Resub to Hum Fert 22/8/11 accepted with minor ammendments 16/11/11 proofs 13/1/12 March 2012 First ever Impact Factor now released 1.377 Read More: http://informahealthcare.com/loi/huf

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KW - Embryo grading

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Embryo morphology as a predictor of IVF success: An evaluation of the proposed UK ACE grading scheme for cleavage stage embryos

Abstract

Keywords

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