TY - JOUR
T1 - Embryonal rhabdomyosarcoma masquerading as a left vocal cord granuloma
AU - Linton, Stefan
AU - Stapleton, E
AU - Penney, Susannah
AU - Sharma, MP
PY - 2020/10/30
Y1 - 2020/10/30
N2 - Embryonal rhabdomyosarcoma (ERMS) of the larynx in adults is an extremely rare diagnosis with insidious onset and progression. Only six reports (including this one) have been documented in the literature. Clinical presentation is dependent on the site, size, subtype of ERMS and growth rate. Hoarseness is the usual first symptom, followed by stridor and dyspnoea, with dysphagia being late in onset. Accurate staging and risk stratification is necessary to avoid overtreating/undertreating patients and should be guided by local Head and Neck/Sarcoma Multidisciplinary Teams. Treatment has moved away from radical therapeutic regimens to less-invasive, organ-preserving therapies. Long-term follow-up is required due to the risk of late recurrence.
AB - Embryonal rhabdomyosarcoma (ERMS) of the larynx in adults is an extremely rare diagnosis with insidious onset and progression. Only six reports (including this one) have been documented in the literature. Clinical presentation is dependent on the site, size, subtype of ERMS and growth rate. Hoarseness is the usual first symptom, followed by stridor and dyspnoea, with dysphagia being late in onset. Accurate staging and risk stratification is necessary to avoid overtreating/undertreating patients and should be guided by local Head and Neck/Sarcoma Multidisciplinary Teams. Treatment has moved away from radical therapeutic regimens to less-invasive, organ-preserving therapies. Long-term follow-up is required due to the risk of late recurrence.
UR - http://europepmc.org/abstract/med/33127702
U2 - 10.1136/bcr-2020-237025
DO - 10.1136/bcr-2020-237025
M3 - Article
C2 - 33127702
SN - 1757-790X
VL - 13
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 10
M1 - e237025
ER -