Recent drug discovery developments in the field of small molecule targeted agents have led to much interest in combining these with radiotherapy. There are good preclinical data to suggest this approach worthy of investigation and in this review we discuss how this has translated into recent clinical trials. The outcome of clinical trials investigating radiotherapy/targeted drug combinations published in the last 5 years is discussed, as are trials in progress. The perceived future opportunities and challenges in the development of this exciting area are considered.
|Number of pages||10|
|Journal||Clinical oncology (Royal College of Radiologists (Great Britain))|
|Publication status||Published - May 2014|
- Molecularly targeted drugs